Swaak A J, Frankfort I, Menon R S, Pekelharing J M, Planten O
Rheumatol Int. 1986;6(4):145-9. doi: 10.1007/BF00541280.
In 40 patients with ankylosing spondylitis (AS) no evidence for IgA nephropathy was obtained. This conclusion was based on the absence of hematuria and on the inability to find an increased incidence of IgA-containing immunoglobulin deposits in skin biopsies. Increased Clq binding assay was only found in those AS patients with anterior uveitis. In 26% of the skin biopsies perivascular mononuclear cell infiltrates were observed, and immunoglobulin deposits were seen in 65%. These facts suggest that the immunologic system is involved in the pathogenesis of this disease.
在40例强直性脊柱炎（AS）患者中，未发现IgA肾病的证据。这一结论基于无血尿以及在皮肤活检中未能发现含IgA免疫球蛋白沉积发生率增加。补体C1q结合试验升高仅在那些患有前葡萄膜炎的AS患者中发现。在26%的皮肤活检中观察到血管周围单核细胞浸润，65%可见免疫球蛋白沉积。这些事实表明免疫系统参与了该疾病的发病机制。
