Dixon J S, Bird H A, Wright V
Ann Rheum Dis. 1981 Aug;40(4):404-8. doi: 10.1136/ard.40.4.404.
The serum biochemistry of 31 patients with ankylosing spondylitis (AS) was compared with that of 80 patients with rheumatoid arthritis (RA) (ARA criteria), 30 of whom were negative for circulating rheumatoid factor and 50 of whom were 'seropositive'. All patients were selected because of moderate to severe disease activity. All 3 groups had distinctive biochemical profiles. Total serum sulphydryl and haemoglobin were particularly good discriminators between AS and RA, IgG, IgA, and acute-phase reactants complemented the sheep cell agglutination test in discriminating between seropositive RA and seronegative RA. In active AS a normal erythrocyte sedimentation rate was often seen in the presence of abnormal C-reactive protein (CRP) and plasma viscosity.
将31例强直性脊柱炎（AS）患者的血清生化指标与80例类风湿关节炎（RA）（ARA标准）患者进行比较，其中30例循环类风湿因子阴性，50例“血清阳性”。所有患者均因中度至重度疾病活动而入选。所有3组都有独特的生化特征。血清总巯基和血红蛋白是区分AS和RA的特别好的指标，IgG、IgA和急性期反应物在区分血清阳性RA和血清阴性RA方面补充了绵羊细胞凝集试验。在活动性AS中，即使红细胞沉降率正常，C反应蛋白（CRP）和血浆粘度也常异常。
