Yuan Fumei, Wang Hong
Department of Martial Art, Wuhan Sports University, Wuhan, China.
Front Aging Neurosci. 2025 Aug 19;17:1612913. doi: 10.3389/fnagi.2025.1612913. eCollection 2025.
To systematically assess the impact of TCE on the efficacy of interventions targeting motor symptoms and mobility in people with Parkinson's disease.
a computerized search was performed for randomized controlled trials assessing TCE intervention for motor symptoms and mobility in Parkinson's disease patients across PubMed, Web of Science, Embase, Cochrane Library, EBSCO, China National Knowledge Infrastructure (CNKI), WanFang data, and VIP database, covering the period from the inception of the databases to January 2025.
fourteen publications encompassing 833 Parkinson's disease patients were incorporated into the literature. A meta-analysis indicated that TCE enhanced the UPDRS-III score (MD = -4.38, 95% CI [-5.95, -2.81]), TUGT score (MD = -2.78, 95% CI [-4.02, -1.54]), and BBS score (MD = 3.68, 95% CI [2.09, 5.27]). The effect size was compared with the Minimum Clinically Important Difference (MCID), and it was found that patients could perceive the alleviation of motor symptoms (UPDRS-III). Subgroup analyses indicated that for motor symptoms (UPDRS-III), the optimal exercise regimen was Qigong (MD = -5.54) with an exercise duration of <12 weeks (MD = -4.79), <3times/week (MD = -4.67), and each session duration ≥60 min (MD = -4.86). For functional walking ability (TUGT), the optimal exercise was Tai Chi (MD = -3.41) with an exercise duration of ≥12 weeks (MD = -3.81), exercise frequency <3times/week (MD = -3.04), and each session duration ≥60 min (MD = -3.05). For balance (BBS), the optimal exercise was also Tai Chi (MD = 5.03) with an exercise duration of ≥12 weeks (MD = 3.75), <3times/week (MD = 3.73) and session duration of ≥60 min (MD = 4.16).
This meta-analysis indicates, the TCE intervention enhances motor symptoms and mobility in people with PD, with optimal outcomes observed from exercise frequency <3times/week, each session duration ≥60 min. The duration of the patient's disease and the intervention group type influenced the effect size (MD).
系统评估太极拳对帕金森病患者运动症状及活动能力干预效果的影响。
通过计算机检索PubMed、Web of Science、Embase、Cochrane图书馆、EBSCO、中国知网（CNKI）、万方数据和维普数据库，检索评估太极拳对帕金森病患者运动症状及活动能力干预效果的随机对照试验，检索时间范围为各数据库建库至2025年1月。
纳入14篇文献，共833例帕金森病患者。Meta分析结果显示，太极拳可提高帕金森病统一评分量表第三部分（UPDRS-III）得分（MD=-4.38，95%CI[-5.95，-2.81]）、定时起立步行测试（TUGT）得分（MD=-2.78，95%CI[-4.02，-1.54]）和伯格平衡量表（BBS）得分（MD=3.68，95%CI[2.09，5.27]）。将效应量与最小临床重要差异（MCID）进行比较，发现患者能感知到运动症状（UPDRS-III）的缓解。亚组分析表明，对于运动症状（UPDRS-III），最佳运动方案为气功（MD=-5.54），运动持续时间<12周（MD=-4.79）、每周<3次（MD=-4.67）、每次运动持续时间≥60分钟（MD=-4.86）。对于功能性步行能力（TUGT），最佳运动为太极拳（MD=-3.41），运动持续时间≥12周（MD=-3.81）、运动频率<3次/周（MD=-3.04）、每次运动持续时间≥60分钟（MD=-3.05）。对于平衡能力（BBS），最佳运动也是太极拳（MD=5.03），运动持续时间≥12周（MD=3.75）、每周<3次（MD=3.73）、每次运动持续时间≥60分钟（MD=4.16）。
本Meta分析表明，太极拳干预可改善帕金森病患者的运动症状及活动能力，每周运动频率<3次、每次运动持续时间≥60分钟时效果最佳。患者病程及干预组类型对效应量（MD）有影响。
