Suzuki Yuriko, Clement Patricia, Dai Weiying, Dolui Sudipto, Fernández-Seara Maria A, Lindner Thomas, Mutsaerts Henk J M M, Petr Jan, Shao Xingfeng, Taso Manuel, Thomas David L
Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
Department of Medical Imaging, Ghent University Hospital, Ghent, Belgium.
Magn Reson Med. 2024 May;91(5):1743-1760. doi: 10.1002/mrm.29815. Epub 2023 Oct 24.
The 2015 consensus statement published by the International Society for Magnetic Resonance in Medicine (ISMRM) Perfusion Study Group and the European Cooperation in Science and Technology ( COST) Action ASL in Dementia aimed to encourage the implementation of robust arterial spin labeling (ASL) perfusion MRI for clinical applications and promote consistency across scanner types, sites, and studies. Subsequently, the recommended 3D pseudo-continuous ASL sequence has been implemented by most major MRI manufacturers. However, ASL remains a rapidly and widely developing field, leading inevitably to further divergence of the technique and its associated terminology, which could cause confusion and hamper research reproducibility. On behalf of the ISMRM Perfusion Study Group, and as part of the ISMRM Open Science Initiative for Perfusion Imaging (OSIPI), the ASL Lexicon Task Force has been working on the development of an ASL Lexicon and Reporting Recommendations for perfusion imaging and analysis, aiming to (1) develop standardized, consensus nomenclature and terminology for the broad range of ASL imaging techniques and parameters, as well as for the physiological constants required for quantitative analysis; and (2) provide a community-endorsed recommendation of the imaging parameters that we encourage authors to include when describing ASL methods in scientific reports/papers. In this paper, the sequences and parameters in (pseudo-)continuous ASL, pulsed ASL, velocity-selective ASL, and multi-timepoint ASL for brain perfusion imaging are included. However, the content of the lexicon is not intended to be limited to these techniques, and this paper provides the foundation for a growing online inventory that will be extended by the community as further methods and improvements are developed and established.
国际医学磁共振学会（ISMRM）灌注研究小组和欧洲科技合作组织（COST）痴呆症领域动脉自旋标记（ASL）行动于2015年发表的共识声明旨在鼓励将稳健的动脉自旋标记灌注磁共振成像（MRI）应用于临床，并促进不同扫描仪类型、地点和研究之间的一致性。随后，大多数主要的MRI制造商都采用了推荐的三维伪连续ASL序列。然而，ASL仍然是一个快速且广泛发展的领域，这不可避免地导致该技术及其相关术语的进一步分化，可能会造成混淆并阻碍研究的可重复性。代表ISMRM灌注研究小组，并作为ISMRM灌注成像开放科学倡议（OSIPI）的一部分，ASL词汇工作组一直在致力于开发ASL词汇以及灌注成像和分析的报告建议，目的是：（1）为广泛的ASL成像技术和参数以及定量分析所需的生理常数制定标准化的、达成共识的命名法和术语；（2）提供一份得到业界认可的成像参数建议，鼓励作者在科学报告/论文中描述ASL方法时纳入这些参数。本文纳入了用于脑灌注成像的（伪）连续ASL、脉冲ASL、速度选择性ASL和多时间点ASL中的序列和参数。然而，词汇的内容并不局限于这些技术，本文为一个不断增长的在线清单奠定了基础，随着更多方法的开发和确立，该清单将由业界进行扩展。
