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食用单宁酸对骨矿化的影响。

The Impact of Tannic Acid Consumption on Bone Mineralization.

作者信息

Winiarska-Mieczan Anna, Muszyński Siemowit, Tomaszewska Ewa, Kwiecień Małgorzata, Donaldson Janine, Tomczyk-Warunek Agnieszka, Blicharski Tomasz

机构信息

Department of Bromatology and Food Physiology, Institute of Animal Nutrition and Bromatology, University of Life Sciences in Lublin, 20-950 Lublin, Poland.

Department of Biophysics, University of Life Sciences in Lublin, 20-950 Lublin, Poland.

出版信息

Metabolites. 2023 Oct 12;13(10):1072. doi: 10.3390/metabo13101072.

Abstract

Tannic acid (TA) is an organic compound belonging to the tannin group. Like other tannins, it has an affinity for endogenous proteins, including digestive enzymes, which can result in the reduced digestibility and absorption of nutrients. It can also form complexes with mineral components, reducing their absorption. In some cases, this can be beneficial, such as in the case of toxic metals, but sometimes it may have a detrimental effect on the body when it involves essential mineral components like Ca, P, Mg, Na, K, or Fe. Therefore, the impact of TA on bone health should be considered from both perspectives. This relatively short review summarizes the available information and research findings on TA, with a particular focus on its potential impact on bone health. It is worth noting that future research and clinical studies may provide more detailed and precise information on this topic, allowing for a better understanding of the role of TA in maintaining the integrity of the musculoskeletal system. Despite its brevity, this paper represents a valuable contribution to the analysis of the potential benefits and challenges associated with TA in the context of bone health. We anticipate that future research will continue along this important research line, expanding our knowledge of the influence of this compound on the skeletal system and its potential therapeutic applications.

摘要

单宁酸(TA)是一种属于单宁类的有机化合物。与其他单宁一样,它对包括消化酶在内的内源性蛋白质具有亲和力,这可能导致营养物质的消化率和吸收率降低。它还能与矿物质成分形成复合物,减少其吸收。在某些情况下,这可能是有益的,比如对于有毒金属而言,但当涉及钙、磷、镁、钠、钾或铁等必需矿物质成分时,有时可能会对身体产生有害影响。因此,应从这两个角度考虑TA对骨骼健康的影响。这篇相对简短的综述总结了关于TA的现有信息和研究结果,特别关注其对骨骼健康的潜在影响。值得注意的是,未来的研究和临床研究可能会提供关于这个主题更详细和精确的信息,从而能更好地理解TA在维持肌肉骨骼系统完整性中的作用。尽管篇幅简短,但本文对分析TA在骨骼健康背景下的潜在益处和挑战做出了有价值的贡献。我们预计未来的研究将继续沿着这条重要的研究路线进行,扩大我们对这种化合物对骨骼系统的影响及其潜在治疗应用的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa7e/10609055/fa1e7129a870/metabolites-13-01072-g001.jpg

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