Gavrilovici Cristina, Spoială Elena-Lia, Miron Ingrith-Crenguţa, Stârcea Iuliana Magdalena, Haliţchi Codruţa Olimpiada Iliescu, Zetu Irina Nicoleta, Lupu Vasile Valeriu, Pânzaru Carmen
Department of Pediatrics, "Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.
"St Mary" Emergency Hospital for Children, 700309 Iasi, Romania.
Microorganisms. 2022 Aug 8;10(8):1598. doi: 10.3390/microorganisms10081598.
Acute otitis media (AOM) is a leading cause of antibiotic prescriptions in children worldwide, even in the era of pneumococcal conjugate vaccines. We aimed to assess the bacterial spectrum of AOM in children and to investigate the antimicrobial resistance profile in culture-positive cases. We performed a retrospective, tympanocentesis-based analysis of antimicrobial resistance patterns in children with AOM hospitalized in "St Mary" Emergency Hospital for Children Iasi, Romania, between January 2013 and December 2021. A total of 147 samples have been assessed, 97 (65.98%) of which had positive cultures, with and as the most common microorganisms. A worrying proportion, 82.85% (58/70), of the strains were multidrug-resistant. The World Health Organization included and on the medium priority group due to penicillin non-susceptibility and ampicillin-resistant strains, respectively. Consequently, strategies to address the threats of antimicrobial resistance are needed to reduce the potential negative effects on hospitalization costs.
急性中耳炎（AOM）是全球儿童抗生素处方的主要原因，即使在肺炎球菌结合疫苗时代也是如此。我们旨在评估儿童AOM的细菌谱，并调查培养阳性病例中的抗菌药物耐药情况。我们对2013年1月至2021年12月期间在罗马尼亚雅西“圣玛丽”儿童医院急诊住院的AOM儿童进行了一项基于鼓膜穿刺术的抗菌药物耐药模式回顾性分析。共评估了147份样本，其中97份（65.98%）培养结果为阳性， 和 是最常见的微生物。令人担忧的是，82.85%（58/70）的 菌株对多种药物耐药。世界卫生组织分别由于青霉素不敏感和氨苄西林耐药菌株，将 和 列入中等优先级组。因此，需要采取策略应对抗菌药物耐药的威胁，以减少对住院费用的潜在负面影响。
