Sankhuu Yanjmaa, Altaisaikhan Odgarig, Battsogt Munkh-Od, Byambasukh Oyuntugs, Khasag Altaisaikhan
Department of Endocrinology, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar 13270, Mongolia.
Department of Endocrinology and Diabetes, First Central Hospital of Mongolia, Ulaanbaatar 210648, Mongolia.
J Clin Med. 2023 Oct 23;12(20):6687. doi: 10.3390/jcm12206687.
(1) Background: Given the growing global diabetes crisis, this study examined the causes of mortality in diabetic patients at a Mongolian tertiary care hospital. (2) Between 2017 and 2021, data from 100 individuals with diabetes (53% male, mean age 58.5 years, duration of diabetes, 9.6 years, HbA1c level, 9.7%, 11.1% type 1 diabetes) were reviewed. (3) Results: The predominant cause of mortality was sepsis, accounting for 65.0% of cases and emerging as a contributing factor in 75.0% of instances. Renal failure constituted the second leading cause of death, accounting for 19.0% of mortalities. Other contributing factors included chronic liver disease (6.0%) and ARDS (3.0%). Regarding sepsis, the individuals affected were relatively younger (57.5 ± 11.2 vs. 61.7 ± 11.2, = 0.988), with a slightly higher prevalence among female patients (77.4%) and those with T1DM (81.8%), though these differences were not statistically significant ( > 0.05). Patients with sepsis exhibited lower BMI values (26.7 ± 4.1 vs. 28.5 ± 6.2, = 0.014) and poorer glycemic control (9.8 ± 3.1 vs. 9.6 ± 5.1, = 0.008); (4) Conclusions: This hospital-based data analysis in Mongolia highlights sepsis as the primary cause of mortality among diabetes patients in tertiary hospitals regardless of age, gender, or diabetes type while also indicating a potential association between a lower BMI, poor glycemic control, smoking, and the risk of sepsis.
(1) 背景：鉴于全球糖尿病危机日益严重，本研究调查了蒙古一家三级护理医院糖尿病患者的死亡原因。(2) 回顾了2017年至2021年期间100例糖尿病患者的数据（男性占53%，平均年龄58.5岁，糖尿病病程9.6年，糖化血红蛋白水平9.7%，1型糖尿病占11.1%）。(3) 结果：主要死亡原因是败血症，占病例的65.0%，在75.0%的病例中是一个促成因素。肾衰竭是第二大死亡原因，占死亡人数的19.0%。其他促成因素包括慢性肝病（6.0%）和急性呼吸窘迫综合征（3.0%）。关于败血症，受影响的个体相对年轻（57.5±11.2岁对61.7±11.2岁，P = 0.988），女性患者（77.4%）和1型糖尿病患者（81.8%）中的患病率略高，尽管这些差异无统计学意义（P>0.05）。败血症患者的体重指数值较低（26.7±4.1对28.5±6.2，P = 0.014），血糖控制较差（9.8±3.1对9.6±5.1，P = 0.008）；(4) 结论：这项基于蒙古医院的数据分析强调，败血症是三级医院糖尿病患者死亡的主要原因，与年龄、性别或糖尿病类型无关，同时也表明较低的体重指数、血糖控制不佳、吸烟与败血症风险之间可能存在关联。
