Dembitsky Valery M
Centre for Applied Research, Innovation and Entrepreneurship, Lethbridge College, 3000 College Drive South, Lethbridge, AB T1K 1L6, Canada.
Biomedicines. 2023 Oct 3;11(10):2698. doi: 10.3390/biomedicines11102698.
Heteroatom steroids, a diverse class of organic compounds, have attracted significant attention in the field of medicinal chemistry and drug discovery. The biological profiles of heteroatom steroids are of considerable interest to chemists, biologists, pharmacologists, and the pharmaceutical industry. These compounds have shown promise as potential therapeutic agents in the treatment of various diseases, such as cancer, infectious diseases, cardiovascular disorders, and neurodegenerative conditions. Moreover, the incorporation of heteroatoms has led to the development of targeted drug delivery systems, prodrugs, and other innovative pharmaceutical approaches. Heteroatom steroids represent a fascinating area of research, bridging the fields of organic chemistry, medicinal chemistry, and pharmacology. The exploration of their chemical diversity and biological activities holds promise for the discovery of novel drug candidates and the development of more effective and targeted treatments.
杂原子甾体是一类多样的有机化合物,在药物化学和药物发现领域引起了广泛关注。杂原子甾体的生物学特性引起了化学家、生物学家、药理学家和制药行业的极大兴趣。这些化合物在治疗各种疾病,如癌症、传染病、心血管疾病和神经退行性疾病方面显示出作为潜在治疗剂的前景。此外,杂原子的引入导致了靶向药物递送系统、前药和其他创新制药方法的发展。杂原子甾体代表了一个引人入胜的研究领域,连接了有机化学、药物化学和药理学领域。对其化学多样性和生物活性的探索有望发现新的候选药物,并开发出更有效、更具针对性的治疗方法。