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一项关于临床因素和调整后的三重 D 系统对 ESWL 成功率影响的前瞻性研究。

A Prospective Study on the Impact of Clinical Factors and Adjusted Triple D System for Success Rate of ESWL.

机构信息

Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, 03225 Vilnius, Lithuania.

Institute of Chemical Physics, Faculty of Physics, Vilnius University, 10222 Vilnius, Lithuania.

出版信息

Medicina (Kaunas). 2023 Oct 13;59(10):1827. doi: 10.3390/medicina59101827.

Abstract

: Our study aimed to evaluate the success rate of ESWL and identify relevant treatment-specific factors affecting treatment outcomes, as well as to assess the accuracy of the updated Triple D scoring system and compare it with older systems. : A prospective study of 71 patients who received ESWL treatment for renal stones that were 5-15 mm in size was completed. The patient having no residual stones or residual stones lesser than 4 mm after ESWL was identified as a treatment success. Univariate and multivariate logistic regression and ROC curves were used to identify important factors for treatment outcomes. : Successful treatment was achieved for 66.2% of patients. The stone volume (SV), mean stone density (MD), and delivered power to the stone volume unit ratio (SMLI/SV) were defined as the most critical factors influencing ESWL success. An updated Triple D score system with a, SMLI/SV ratio could be an alternative to older systems and reach an even higher accuracy. A limitation of this study is the limited sample size due to the COVID-19 pandemic. : Our results show that the three factors that most influence the success of ESWL are the stone size, mean stone density, and SMLI/SV ratio. Based on this, we present a simple updated triple D score system to predict ESWL success, which could be implemented in future clinical practice.

摘要

: 本研究旨在评估 ESWL 的成功率,并确定影响治疗结果的相关治疗特异性因素,同时评估更新的 Triple D 评分系统的准确性,并将其与旧系统进行比较。: 对 71 例接受 5-15mm 大小肾结石 ESWL 治疗的患者进行了前瞻性研究。将 ESWL 治疗后无残留结石或残留结石小于 4mm 的患者视为治疗成功。采用单因素和多因素逻辑回归及 ROC 曲线分析治疗结果的重要因素。: 66.2%的患者治疗成功。结石体积(SV)、平均结石密度(MD)和单位结石体积传递功率比(SMLI/SV)被定义为影响 ESWL 成功的最关键因素。具有 SMLI/SV 比值的更新的 Triple D 评分系统可能是旧系统的替代方案,并且可以达到更高的准确性。本研究的一个局限性是由于 COVID-19 大流行,样本量有限。: 我们的研究结果表明,影响 ESWL 成功率的三个最重要因素是结石大小、平均结石密度和 SMLI/SV 比值。基于此,我们提出了一种简单的更新的 Triple D 评分系统来预测 ESWL 成功率,这可以在未来的临床实践中实施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06e3/10608682/83731ee39edc/medicina-59-01827-g001.jpg

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