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通过简单增加肾内位置来强化三联D评分,以预测直径为10至20毫米的肾结石冲击波碎石术后的无石率。

Reinforcement of the Triple D score with simple addition of the intrarenal location for the prediction of the stone-free rate after shockwave lithotripsy for renal stones 10-20 mm in diameter.

作者信息

Ichiyanagi Osamu, Fukuhara Hiroki, Kurokawa Masayuki, Izumi Takuji, Suzuki Hitoshi, Naito Sei, Nishida Hayato, Kato Tomoyuki, Tsuchiya Norihiko

机构信息

Department of Urology, Yamagata University Faculty of Medicine, 2-2-2 Iida-nishi, Yamagata, 998-9585, Japan.

Department of Urology, Yamagata Prefectural Kahoku Hospital, 111 Aza-Gassando, Yachi, Kahoku, 999-3511, Japan.

出版信息

Int Urol Nephrol. 2019 Feb;51(2):239-245. doi: 10.1007/s11255-018-02066-1. Epub 2019 Jan 2.

Abstract

PURPOSE

We investigated the clinical efficacy of the Triple D score (TrD-S) on stone-free rate (SFR) prediction following shockwave lithotripsy (SWL) for renal stones 10-20 mm in diameter and modified the scoring system to improve outcome prediction.

METHODS

We retrospectively examined clinical data from the medical records of 226 consecutive patients who underwent SWL for 10-20 mm kidney stones. The TrD-S was calculated according to the cutoffs of < 150 mm for stone volume, < 600 Hounsfield unit for stone density, and < 12 cm for skin-to-stone distance on computed tomography. The Quadruple D score was defined as the sum of the TrD-S and stone location (0/1 point for intrarenal stone distribution at lower/non-lower poles, respectively). Complete clearance 3 months after the final SWL was considered the stone-free status.

RESULTS

The residual group (n = 102) had significantly older age, larger stones, higher stone density, higher lower-pole stone incidence, and lower TrD-S than the stone-free group (n = 124). In the multivariate analysis, age, TrD-S, and non-lower-pole stones independently predicted the SFR. The TrD-Ss of 0, 1, 2, and 3 points showed SFRs of 40.0%, 51.9%, 73.0%, and 100.0%, respectively. The Quadruple D scores of 0, 1, 2, 3, and 4 points showed SFRs of 0.0%, 37.9%, 54.5%, 84.4%, and 100.0%, respectively, with better prediction accuracy than the TrD-S (p = 0.01).

CONCLUSIONS

The TrD-S is successfully validated for use in Japanese patients with 10-20-mm renal stones. Simple addition of the stone location to the TrD-S could reinforce SFR prediction after SWL.

摘要

目的

我们研究了三联D评分(TrD-S)对直径10 - 20毫米肾结石冲击波碎石术(SWL)后结石清除率(SFR)预测的临床疗效,并对评分系统进行了修改以改善结局预测。

方法

我们回顾性检查了226例连续接受SWL治疗10 - 20毫米肾结石患者的病历临床资料。根据计算机断层扫描中结石体积<150立方毫米、结石密度<600亨氏单位以及皮肤到结石距离<12厘米的临界值计算TrD-S。四联D评分定义为TrD-S与结石位置之和(肾内结石分布于下极/非下极分别为0/1分)。最后一次SWL后3个月的完全清除被视为无结石状态。

结果

残留组(n = 102)比无结石组(n = 124)年龄显著更大、结石更大、结石密度更高、下极结石发生率更高且TrD-S更低。在多变量分析中,年龄、TrD-S和非下极结石独立预测SFR。TrD-S评分为0、1、2和3分的SFR分别为40.0%、51.9%、73.0%和100.0%。四联D评分为0、1、2、3和4分的SFR分别为0.0%、37.9%、54.5%、84.4%和100.0%,预测准确性优于TrD-S(p = 0.01)。

结论

TrD-S在日本10 - 20毫米肾结石患者中成功验证可使用。在TrD-S基础上简单增加结石位置可加强SWL后SFR的预测。

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