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抗菌药物给药途径对断奶仔猪生长及抗菌药物耐药性的影响

Effects of Antimicrobial Administration Route on Growth and Antimicrobial Resistance in Weaned Piglets.

作者信息

Lee Seong-Won, Jung Chang-Min, Do Kyung-Hyo, Lee Wan-Kyu, Seo Kwang-Won

机构信息

Boehringer Ingelheim Animal Health Korea Ltd., Yonsei Severance Bldg. 16F, 10 Tongil-ro, Jung-gu, Seoul 04527, Republic of Korea.

College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Republic of Korea.

出版信息

Animals (Basel). 2023 Oct 19;13(20):3264. doi: 10.3390/ani13203264.

DOI:10.3390/ani13203264
PMID:37893988
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10603663/
Abstract

This study aimed to determine how the route of antimicrobial administration affected the growth performance of weaned piglets. Additionally, we aimed to investigate potential differences between antimicrobial resistance developed by antimicrobials administered orally through drinking water, and those administered through feed, in weaned piglets. The research was undertaken on a farm housing 500 sows and involved 150 weaned piglets at 21 days of age. These piglets were evenly distributed into three groups of equal size: water, feed, and control. Antimicrobials were administered through drinking water and feed in the water and feed groups, respectively, while the control group received no antimicrobial treatment. The observation of piglets continued until they reached 70 days of age. The feed conversion ratio in the water group (1.7 ± 0.78) was significantly higher than in the control (2.4 ± 1.77) and feed (2.7 ± 1.68) groups. Additionally, the route of administration did not affect antimicrobial resistance rates. Based on these results, it can be inferred that administering antimicrobials through drinking water is advantageous for pig farming.

摘要

本研究旨在确定抗菌药物的给药途径如何影响断奶仔猪的生长性能。此外,我们旨在调查断奶仔猪通过饮水口服给药与通过饲料给药所产生的抗菌药物耐药性之间的潜在差异。该研究在一个饲养500头母猪的农场进行,涉及150头21日龄的断奶仔猪。这些仔猪被均匀地分为三组,每组大小相等:饮水组、饲料组和对照组。抗菌药物分别通过饮水和饲料给予饮水组和饲料组的仔猪,而对照组不接受抗菌药物治疗。对仔猪的观察持续到它们达到70日龄。饮水组的饲料转化率(1.7±0.78)显著高于对照组(2.4±1.77)和饲料组(2.7±1.68)。此外,给药途径不影响抗菌药物耐药率。基于这些结果,可以推断通过饮水给予抗菌药物对养猪业有利。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dc6/10603663/26d5a6ac9546/animals-13-03264-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dc6/10603663/26d5a6ac9546/animals-13-03264-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dc6/10603663/26d5a6ac9546/animals-13-03264-g001.jpg

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Ann Clin Microbiol Antimicrob. 2023 Jan 19;22(1):7. doi: 10.1186/s12941-023-00559-1.
2
Molecular characteristics of fluoroquinolone-resistant Escherichia coli isolated from suckling piglets with colibacillosis.氟喹诺酮类耐药大肠杆菌的分子特征从仔猪大肠杆菌病分离。
BMC Microbiol. 2022 Sep 15;22(1):216. doi: 10.1186/s12866-022-02632-9.
3
Antimicrobial resistance, virulence genes, and phylogenetic characteristics of pathogenic Escherichia coli isolated from patients and swine suffering from diarrhea.
从腹泻的患者和猪中分离出的致病性大肠杆菌的耐药性、毒力基因和系统发育特征。
BMC Microbiol. 2022 Aug 16;22(1):199. doi: 10.1186/s12866-022-02604-z.
4
Antimicrobial Resistance, Serologic and Molecular Characterization of Isolated from Calves with Severe or Fatal Enteritis in Bavaria, Germany.从德国巴伐利亚州患有严重或致命肠炎的犊牛中分离出的[微生物名称]的抗菌药物耐药性、血清学及分子特征分析 (注:原文中“Isolated from...”前应该有具体的微生物名称,这里翻译为“[微生物名称]”)
Antibiotics (Basel). 2021 Dec 27;11(1):23. doi: 10.3390/antibiotics11010023.
5
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Animals (Basel). 2021 Nov 4;11(11):3144. doi: 10.3390/ani11113144.
6
Plasmid-Encoded AmpC and Extended-Spectrum Beta-Lactamases in Multidrug-Resistant Isolated from Piglets in Portugal.质粒介导的 AmpC 和超广谱β-内酰胺酶在葡萄牙仔猪分离的多药耐药菌中的研究
Microb Drug Resist. 2021 Dec;27(12):1742-1749. doi: 10.1089/mdr.2020.0387. Epub 2021 Jun 29.
7
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Vet Microbiol. 2021 Jul;258:109125. doi: 10.1016/j.vetmic.2021.109125. Epub 2021 May 15.
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Antibiotics (Basel). 2020 Oct 29;9(11):755. doi: 10.3390/antibiotics9110755.
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Front Microbiol. 2020 May 25;11:861. doi: 10.3389/fmicb.2020.00861. eCollection 2020.
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Microorganisms. 2020 Feb 17;8(2):269. doi: 10.3390/microorganisms8020269.