Paduraru Ana Alexandra, Lupu Maria Alina, Sima Laurentiu, Cozma Gabriel Veniamin, Olariu Sorin Dan, Chiriac Sorin Dan, Totolici Bogdan Dan, Pirvu Catalin Alexandru, Lazar Fulger, Nesiu Alexandru, Mihu Alin Gabriel, Cumpanas Alin Adrian, Cretu Octavian Marius, Olariu Tudor Rares
Discipline of Parasitology, Department of Infectious Diseases, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Center for Diagnosis and Study of Parasitic Diseases, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Microorganisms. 2023 Sep 25;11(10):2388. doi: 10.3390/microorganisms11102388.
Cystic echinococcosis (CE) is a neglected parasitic disease caused by the tapeworm . The aim of this study was to assess the epidemiological features of human cystic echinococcosis in patients from Western Romania. We retrospectively investigated the medical records of patients hospitalized with CE between 1 January 2007 and 1 September 2022. A total of 366 patients (range 18-90 years) were recorded. The number of hospitalized individuals was higher in patients aged 50-59 years (83/366, 22.7%), in females (194/366, 53%), and in residents of rural areas (225/366, 61.5%). The liver was the most common localization of the cysts (302/366, 82.5%). Ninety-eight patients (26.8%) presented complications, including biliary fistula, allergies, and infection of the cyst. Patients with complications had a longer mean hospital stay (15.7 ± 8.3 days) compared to patients without complications (11.5 ± 7.3 days) ( < 0.001). The results of this study revealed that patients diagnosed with CE required hospitalization and extended medical care, indicating that this zoonotic disease remains a significant public health problem in Western Romania. Public health authorities should enhance CE surveillance by implementing control programs and mandatory notification of new cases.
囊型包虫病（CE）是一种由绦虫引起的被忽视的寄生虫病。本研究的目的是评估罗马尼亚西部患者的人类囊型包虫病的流行病学特征。我们回顾性调查了2007年1月1日至2022年9月1日期间因CE住院患者的病历。共记录了366例患者（年龄范围18 - 90岁）。50 - 59岁患者（83/366，22.7%）、女性患者（194/366，53%）和农村地区居民（225/366，61.5%）的住院人数较多。肝脏是囊肿最常见的寄生部位（302/366，82.5%）。98例患者（26.8%）出现并发症，包括胆瘘、过敏和囊肿感染。与无并发症患者（11.5±7.3天）相比，有并发症的患者平均住院时间更长（15.7±8.3天）（<0.001）。本研究结果表明，被诊断为CE的患者需要住院治疗和长期医疗护理，这表明这种人畜共患病在罗马尼亚西部仍然是一个重大的公共卫生问题。公共卫生当局应通过实施控制计划和强制报告新病例来加强CE监测。
