Malekpour Alamdari Nasser, Ansari Iman, Karimian Maede, Babakhani Elnaz, Hatami Sara, Mohammadsadeghi Parisa, Abbasi Maryam
Critical Care Quality Improvement Research Center, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of General Surgery, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Iran J Pathol. 2025 Summer;20(3):330-334. doi: 10.30699/ijp.2025.2056341.3430. Epub 2025 Jul 1.
BACKGROUND & OBJECTIVE: This study presents a rare case of hydatid cysts involving the liver, spleen, and peritoneum, in which clinical features and radiologic findings initially raised strong suspicion for abdominal malignancy with peritoneal seeding.
A 64-year-old man presented with vague epigastric pain, weight loss, and iron deficiency anemia. Abdominal ultrasonography revealed multiple splenic lesions suggestive of hydatid cysts. Hydatid serology was negative. Chest CT was unremarkable. Abdominal and pelvic CT showed splenomegaly with cystic lesions, including a calcified cyst in segment VI of the liver. Numerous hypodense peritoneal nodules were identified, particularly in the mid-omentum and supraumbilical region. Differential diagnoses included hydatid disease, primary peritoneal neoplasms, and peritoneal metastases. Due to anemia, weight loss, and the suspicion of peritoneal carcinomatosis, hydatid disease alone could not fully account for the findings, prompting further diagnostic evaluation. Endoscopy and colonoscopy were unremarkable. The patient underwent exploratory laparotomy and splenectomy, along with partial omentectomy where hydatid involvement was suspected. Postoperatively, he was treated with albendazole 800 mg daily and discharged on postoperative day three. At 3- and 6-month follow-ups, the patient reported resolution of abdominal pain, and physical examinations were normal.
Peritoneal hydatid disease is rare and can mimic peritoneal carcinomatosis, leading to diagnostic uncertainty and treatment delay. Surgical excision followed by antiparasitic therapy remains the cornerstone of management.
本研究报告了一例罕见的累及肝脏、脾脏和腹膜的包虫囊肿病例,其临床特征和影像学表现最初强烈怀疑为伴有腹膜种植的腹部恶性肿瘤。
一名64岁男性患者,出现上腹部隐痛、体重减轻和缺铁性贫血。腹部超声检查发现脾脏有多个病变,提示为包虫囊肿。包虫血清学检查为阴性。胸部CT检查未见异常。腹部和盆腔CT显示脾脏肿大,伴有囊性病变,包括肝脏VI段的一个钙化囊肿。发现大量低密度腹膜结节,尤其是在大网膜中部和脐上区域。鉴别诊断包括包虫病、原发性腹膜肿瘤和腹膜转移瘤。由于贫血、体重减轻以及怀疑腹膜癌,仅包虫病无法完全解释这些发现,因此需要进一步的诊断评估。内镜检查和结肠镜检查均未见异常。患者接受了剖腹探查术和脾切除术,以及怀疑有包虫累及部位的部分大网膜切除术。术后,患者每天接受800毫克阿苯达唑治疗,并于术后第三天出院。在3个月和6个月的随访中,患者报告腹痛缓解,体格检查正常。
腹膜包虫病罕见,可酷似腹膜癌,导致诊断不确定和治疗延误。手术切除后进行抗寄生虫治疗仍然是治疗的基石。