Salazar-Gómez Anuar, Velo-Silvestre Amabile A, Alonso-Castro Angel Josabad, Hernández-Zimbrón Luis Fernando
Laboratorio de Investigación Interdisciplinaria, Área de Optomtería, Escuela Nacional de Estudios Superiores Unidad León, Universidad Nacional Autónoma de México (ENES-León UNAM), Blvd. UNAM 2011, Guanajuato 37684, Mexico.
Clínica de Optometría, Escuela Nacional de Estudios Superiores Unidad León, Universidad Nacional Autónoma de México (ENES-León UNAM), Blvd. UNAM 2011, Guanajuato 37684, Mexico.
Pharmaceuticals (Basel). 2023 Oct 9;16(10):1432. doi: 10.3390/ph16101432.
Medicinal plants have been historically significant for treating common human diseases in Mexico. Although some ethnobotanical research exists, limited ethnomedicinal data has documented medicinal plants employed for eye health. This review focuses on ethnomedicinal information and preclinical and clinical studies regarding medicinal plants used in Mexico for treating symptoms associated with eye conditions. An electronic database search was conducted by consulting scientific articles, books about Mexican herbal medicine, and academic theses. This work recorded 69 plant species belonging to 26 plant families, especially plants from the Crassulaceae family, which are used as remedies for irritation and infections in the eye. Eight of these medicinal plants have been the subject of preclinical studies using ocular models, and one medicinal plant has been tested in clinical trials. The evidence of pharmacological effects indicates the promising therapeutic potential of these medicinal plants for developing new treatments for eye conditions. However, toxicological studies are necessary to ensure safe application to the eye, particularly as traditional medicine continues to be relied upon worldwide. In addition, this review highlights the need to perform ethnobotanical and phytochemical studies in Mexico regarding the medicinal flora used as remedies for eye conditions.
药用植物在墨西哥治疗常见人类疾病的历史上具有重要意义。尽管存在一些民族植物学研究,但关于用于眼部健康的药用植物的民族医学数据有限。本综述聚焦于墨西哥用于治疗与眼部疾病相关症状的药用植物的民族医学信息以及临床前和临床研究。通过查阅科学文章、关于墨西哥草药的书籍和学术论文进行了电子数据库搜索。这项工作记录了属于26个植物科的69种植物,尤其是景天科植物,它们被用作治疗眼部刺激和感染的药物。其中8种药用植物已成为使用眼部模型进行临床前研究的对象,1种药用植物已在临床试验中进行了测试。药理作用的证据表明这些药用植物在开发眼部疾病新疗法方面具有广阔的治疗潜力。然而,毒理学研究对于确保眼部安全应用是必要的,特别是在全球范围内继续依赖传统医学的情况下。此外,本综述强调有必要在墨西哥对用作眼部疾病治疗药物的药用植物进行民族植物学和植物化学研究。