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巴西某大学医院人类免疫缺陷病毒/获得性免疫缺陷综合征(HIV/AIDS)延迟诊断的相关因素:实现 2030 年目标的挑战。

Factors Associated with Late Diagnosis of Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) in a University Hospital in Brazil: Challenges to Achieving the 2030 Target.

机构信息

Ribeirão Preto College of Nursing, University of São Paulo, Ribeirão Preto 14040-902, Brazil.

Faculty of Nursing, Federal University of Pará, Belém 66075-110, Brazil.

出版信息

Viruses. 2023 Oct 17;15(10):2097. doi: 10.3390/v15102097.

Abstract

INTRODUCTION

This study aimed to identify factors associated with late diagnosis and clinically monitor newly diagnosed HIV/AIDS patients.

METHOD

Retrospective study, based on secondary data from a specialized unit at the Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto of the University of Sao Paulo. Data collection included sociodemographic, behavioral, clinical, and laboratory data of newly diagnosed HIV patients between 2015 and 2019. Data analysis was undertaken using inferential statistical tests.

RESULTS

A total of 314 individuals were newly diagnosed with HIV/AIDS, 86.6% (272) had a late diagnosis and 53.8% (169) were diagnosed very late. Using the adjusted odds ratio, we observed that bisexual and MSM patients were less likely to have a late diagnosis compared to straight patients. Individuals who entered through the emergency department and Outpatient Clinic had a lower chance of having a very late diagnosis compared to those diagnosed in the ward/inpatient unit. Having a higher education and university education were protective factors against having a very late diagnosis of HIV infection compared to elementary school education only. In addition, male patients were more likely to have a very late diagnosis compared to female patients.

CONCLUSIONS

This study evidenced a high prevalence of late and very late diagnoses. Therefore, attention should be directed towards factors related to late and very late presentation.

摘要

简介

本研究旨在确定与艾滋病病毒/艾滋病新诊断患者的晚期诊断和临床监测相关的因素。

方法

这是一项回顾性研究,基于圣保罗大学里贝朗普雷图医学院临床医院专门科室的二级数据。数据收集包括 2015 年至 2019 年间新诊断为艾滋病病毒的患者的社会人口统计学、行为、临床和实验室数据。数据分析采用推断性统计检验。

结果

共有 314 人新诊断为艾滋病病毒/艾滋病,86.6%(272 人)为晚期诊断,53.8%(169 人)为极晚期诊断。使用调整后的优势比,我们发现双性恋和男男性接触者与异性恋者相比,不太可能出现晚期诊断。与在病房/住院部诊断的患者相比,通过急诊室和门诊就诊的患者出现极晚期诊断的几率较低。与仅接受小学教育的患者相比,接受更高教育和大学教育是预防极晚期感染艾滋病病毒诊断的保护因素。此外,男性患者比女性患者更有可能出现极晚期诊断。

结论

本研究表明,晚期和极晚期诊断的发生率较高。因此,应关注与晚期和极晚期表现相关的因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d12a/10612088/95fd67b43d50/viruses-15-02097-g001.jpg

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