Medical Faculty, University of Leipzig, Leipzig, Germany.
Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig, Germany.
Qual Life Res. 2024 Feb;33(2):387-398. doi: 10.1007/s11136-023-03526-7. Epub 2023 Oct 28.
The present study aims to investigate the prospective effect of depressive symptoms on overall QoL in the oldest age group, taking into account its different facets.
Data were derived from the multicenter prospective AgeCoDe/AgeQualiDe cohort study, including data from follow-up 7-9 and n = 580 individuals 85 years of age and older. Overall QoL and its facets were assessed using the WHOQOL-OLD instrument. The short form of the geriatric depression scale (GDS-15) was applied to assess depressive symptoms. Cognitively impaired individuals were excluded. Linear mixed-effects models were used to assess the effect of depressive symptoms on QoL.
Depressive symptoms were significantly associated with overall QoL and each of the different facets of WHOQOL-OLD, also after adjustment for time and sociodemographic characteristics such as age, gender, education, marital status, living situation, and cognitive status. Higher age and single as well as divorced marital status were also associated with a lower QoL.
This work provides comprehensive longitudinal results on the relationship between depressive symptoms and QoL in the oldest age population. The results underscore the relevance of tailored and targeted care planning and the development of customized interventions.
本研究旨在探讨抑郁症状对最年长人群总体生活质量的前瞻性影响，同时考虑其不同方面。
数据来自多中心前瞻性 AgeCoDe/AgeQualiDe 队列研究，包括随访 7-9 年的 n=580 名 85 岁及以上个体的数据。使用世界卫生组织生活质量老龄化量表（WHOQOL-OLD）评估总体生活质量及其各方面。采用老年抑郁量表（GDS-15）的简短形式评估抑郁症状。排除认知障碍者。采用线性混合效应模型评估抑郁症状对生活质量的影响。
抑郁症状与 WHOQOL-OLD 的总体生活质量和各个方面显著相关，即使在调整了时间和社会人口学特征（如年龄、性别、教育、婚姻状况、居住状况和认知状况）后也是如此。较高的年龄、单身和离异的婚姻状况也与较低的生活质量相关。
这项工作提供了最年长人群中抑郁症状与生活质量之间关系的全面纵向结果。结果强调了有针对性的护理计划和定制干预措施的制定的重要性。
