Nanevicz T M, Prince M R, Gawande A A, Puliafito C A
Arch Ophthalmol. 1986 Dec;104(12):1825-9. doi: 10.1001/archopht.1986.01050240099048.
Ablation of the bovine crystalline lens was studied using radiation from an excimer laser at four ultraviolet wave lengths as follows: 193 nm (argon fluoride), 248 nm (krypton fluoride), 308 nm (xenon chloride), and 351 nm (xenon fluoride). The ablation process was quantitated by measuring mass ablated with an electronic balance, and characterized by examining ablation craters with scanning electron microscopy. The highest ablation rate was observed at 248 nm with lower rates at 193 and 308 nm. No ablation was observed at 351 nm. Scanning electron microscopy revealed the smoothest craters at 193 nm while at 248 nm there was vacuolization in the crater walls and greater disruption of surrounding tissue. The craters made at 308 nm did not have as smooth a contour as the 193-nm lesions. The spectral absorbance of the bovine lens was calculated at the wavelengths used for ablation and correlated with ablation rates and thresholds. High peak-power, pulsed ultraviolet laser radiation may have a role in surgical removal of the lens.
193纳米（氟化氩）、248纳米（氟化氪）、308纳米（氯化氙）和351纳米（氟化氙）。通过用电子天平测量消融的质量来对消融过程进行定量，并通过扫描电子显微镜检查消融坑来表征该过程。在248纳米处观察到最高的消融率，在193和308纳米处的消融率较低。在351纳米处未观察到消融。扫描电子显微镜显示在193纳米处坑最平滑，而在248纳米处坑壁有空泡形成且周围组织的破坏更大。在308纳米处形成的坑的轮廓不如193纳米处的损伤那样平滑。计算了牛晶状体在用于消融的波长下的光谱吸光度，并将其与消融率和阈值相关联。高峰值功率的脉冲紫外激光辐射可能在晶状体的手术切除中发挥作用。
