Large-scale fabrication of neutron-shielding films with flexible or complex shapes is challenging. Uniform and high boron carbide (BC) filler loads with sufficient workability are needed to achieve good neutron-absorption capacity. Here, we show that a two-dimensional (2D) TiCT MXene hybrid film with homogeneously distributed BC particles exhibits high mechanical flexibility and anomalous neutron-shielding properties. Layered and solution-processable 2D TiCT MXene flakes serve as an ideal robust and flexible matrix for high-content BC fillers (60 wt.%). In addition, the preparation of a scalable neutron shielding MXene/BC hybrid paint is demonstrated. This composite can be directly integrated with various large-scale surfaces (e.g., stainless steel, glass, and nylon). Because of their low thickness, simple and scalable preparation method, and an absorption capacity of 39.8% for neutrons emitted from a Am-Be source, the 2D TiCT MXene hybrid films are promising candidates for use in wearable and lightweight applications.