Department of Pharmaceutical Science, School of Medical and Allied Science, GD Goenka University, Gurugram, Haryana, India.
Curr Protein Pept Sci. 2024;25(3):200-205. doi: 10.2174/0113892037276171231016103320.
Diabetic wound healing is expected to affect 25% of all diabetics, resulting in less severe external factors, economic costs, and less trauma. Topical formulations have been continually improved to achieve a range of amazing properties and have had a significant impact on the management of diabetic wounds. Topical insulin has become one of the most attractive and convenient wound healing techniques due to its excellent biocompatibility, water retention, and therapeutic properties. Multiple versatile topical insulins have been identified and have shown promise over the past few years as they greatly facilitate the management of diabetic wounds as we understand their etiology. The physiological wound healing process repairs damaged tissue and restores skin integrity. For about a century, insulin, a powerful healing agent, and it has been utilized in several clinical and experimental researches research studies to accelerate the healing of various injuries.
糖尿病创面愈合预计将影响所有糖尿病患者的 25%，导致外部因素、经济成本和创伤更小。局部制剂一直在不断改进，以实现一系列惊人的特性，并对糖尿病创面的管理产生了重大影响。由于其出色的生物相容性、保水性和治疗特性，局部胰岛素已成为最具吸引力和方便的创面愈合技术之一。多种多功能局部胰岛素已被确定，并且在过去几年中表现出了希望，因为它们极大地促进了我们对其病因学的理解的糖尿病创面的管理。生理创面愈合过程修复受损组织并恢复皮肤完整性。大约一个世纪以来，胰岛素一直被用作一种强大的愈合剂，并在多项临床和实验研究中被用于加速各种损伤的愈合。
