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脊柱畸形、颈胸交界区手术以及美国麻醉医师协会分级增加了脊柱后路手术后入住外科重症监护病房治疗的风险:一项对962例患者的单中心多因素分析

Spinal Deformity, Surgery at the Cervicothoracic Junction, and American Society of Anesthesiologists Class Increase the Risk of Post-surgical Intensive Care Unit Treatment after Dorsal Spine Surgery: A Single-Center Multivariate Analysis of 962 Patients.

作者信息

Leyendecker Jannik, Prasse Tobias, Rahhal Ahmad Al, Hofstetter Christoph Paul, Wetsch Wolfgang, Eysel Peer, Bredow Jan

机构信息

Department of Orthopaedics and Trauma Surgery, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.

Department of Neurological Surgery, University of Washington, Seattle, WA, USA.

出版信息

Asian Spine J. 2023 Dec;17(6):1035-1042. doi: 10.31616/asj.2023.0093. Epub 2023 Nov 10.

DOI:10.31616/asj.2023.0093
PMID:37946337
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10764134/
Abstract

STUDY DESIGN

This was a retrospective multivariate analysis of preoperative risk factors leading to intensive care unit (ICU) admissions in patients undergoing elective or acute dorsal spine surgery.

PURPOSE

Numerous studies have predicted a substantial increase in spine surgeries within the next decades, potentially overwhelming hospitals' resources, including ICU occupancy. Accurate estimates of whether patients need postsurgical ICU treatment are pivotal for both resource allocation and patient safety.

OVERVIEW OF LITERATURE

Risk factors leading to ICU admissions after dorsal spine surgery have been extensively examined for lumbar elective surgery. Studies including other anatomical segments of the spine and nonelective surgery regarding postsurgical ICU treatment probability are lacking.

METHODS

This study was designed to be a single-center multivariate analysis of data retrospectively collected from a tertiary care university hospital. Patients undergoing dorsal spine surgery from 2009 to 2019 were included in this study. The patients' demographic data were analyzed to determine potential preoperative risk factors for ICU admission after surgery using multiple logistic regression.

RESULTS

In our cohort, 962 patients with a mean age of 71.1±0.55 years were included. Surgeries involved 3.24±0.08 spinal levels on average. The incidence of ICU treatment after surgery was 30.4% (n=292). Multivariate logistic regression showed a markedly increased odds ratio (OR) for patients undergoing surgery of the cervicothoracic junction (OR, 8.86) and those undergoing surgery for spinal deformity treatment (OR, 7.7). Additionally, cervical procedures (OR, 3.29), American Society of Anesthesiologists (ASA) class 3-4 (OR, 2.74), spondylodiscitis (OR, 2.47), fusion of ≥3 levels (OR, 1.94), and age >75 years (OR, 1.33) were associated with an increased risk of postsurgical ICU admission.

CONCLUSIONS

The findings highlight the relevance of anatomical location, preoperative diagnosis, ASA class, and length of surgery regarding the predictability of postoperative ICU admission. Our data allowed for more sophisticated estimates regarding the need for ICU treatment after dorsal spine surgery, guiding the surgeon through patient selection, communication, and ICU admission predictability.

摘要

研究设计

这是一项对接受择期或急性脊柱后路手术患者入住重症监护病房(ICU)的术前风险因素进行的回顾性多变量分析。

目的

众多研究预测,在未来几十年内脊柱手术量将大幅增加,这可能会使包括ICU床位在内的医院资源不堪重负。准确评估患者术后是否需要ICU治疗对于资源分配和患者安全都至关重要。

文献综述

对于腰椎择期手术,导致脊柱后路手术后入住ICU的风险因素已得到广泛研究。但缺乏包含脊柱其他解剖节段以及非择期手术术后入住ICU概率的研究。

方法

本研究旨在对一家三级医疗大学医院回顾性收集的数据进行单中心多变量分析。纳入2009年至2019年接受脊柱后路手术的患者。分析患者的人口统计学数据,使用多因素逻辑回归确定术后入住ICU的潜在术前风险因素。

结果

在我们的队列中,纳入了962例平均年龄为71.1±0.55岁的患者。手术平均涉及3.24±0.08个脊柱节段。术后ICU治疗的发生率为30.4%(n = 292)。多因素逻辑回归显示,接受颈胸交界区手术的患者(比值比[OR],8.86)以及接受脊柱畸形治疗手术的患者(OR,7.7)的比值比显著升高。此外,颈椎手术(OR,3.29)、美国麻醉医师协会(ASA)分级3 - 4级(OR,2.74)、脊椎椎间盘炎(OR,2.47)、≥3个节段融合(OR,1.94)以及年龄>75岁(OR,1.33)与术后入住ICU的风险增加相关。

结论

研究结果突出了解剖位置、术前诊断、ASA分级和手术时长对于预测术后入住ICU的相关性。我们的数据有助于更精确地估计脊柱后路手术后对ICU治疗的需求,在患者选择、沟通以及ICU入住预测方面为外科医生提供指导。

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本文引用的文献

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Living longer, working longer: analysing time trends in working life expectancy in Germany from a health perspective between 2002 and 2018.寿命延长,工作年限延长:从健康角度分析2002年至2018年德国工作预期寿命的时间趋势。
Eur J Ageing. 2022 May 23;19(4):1263-1276. doi: 10.1007/s10433-022-00707-0. eCollection 2022 Dec.
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Does extending a posterior cervical fusion construct into the upper thoracic spine impact patient-reported outcomes as long as 2 years after surgery in patients with degenerative cervical myelopathy?对于患有退行性颈椎脊髓病的患者,将后路颈椎融合结构延伸至上胸椎是否会影响术后长达2年的患者报告结局?
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Longitudinal Trends of Patient Demographics and Morbidity of Different Approaches in Lumbar Interbody Fusion: An Analysis Using the American College of Surgeons National Surgical Quality Improvement Program Database.腰椎体间融合术不同方法患者特征和发病率的纵向趋势:利用美国外科医师学会国家手术质量改进计划数据库进行的分析。
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COVID-19 pandemic and elective spinal surgery cancelations - what happens to the patients?COVID-19 大流行与择期脊柱手术取消——患者会怎样?
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Trends in lumbar spinal fusion-a literature review.腰椎融合术的发展趋势——文献综述
J Spine Surg. 2020 Dec;6(4):752-761. doi: 10.21037/jss-20-492.
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