Institute for Quantitative Biomedicine, Rutgers, State University of New Jersey, 174 Frelinghuysen Road, Piscataway, NJ 08854, USA.
Research Collaboratory for Structural Bioinformatics Protein Data Bank, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.
Nucleic Acids Res. 2024 Jan 5;52(D1):D245-D254. doi: 10.1093/nar/gkad957.
The Nucleic Acid Knowledgebase (nakb.org) is a new data resource, updated weekly, for experimentally determined 3D structures containing DNA and/or RNA nucleic acid polymers and their biological assemblies. NAKB indexes nucleic acid-containing structures derived from all major structure determination methods (X-ray, NMR and EM), including all held by the Protein Data Bank (PDB). As the planned successor to the Nucleic Acid Database (NDB), NAKB's design preserves all functionality of the NDB and provides novel nucleic acid-centric content, including structural and functional annotations, as well as annotations from and links to external resources. A variety of custom interactive tools have been developed to enable rapid exploration and drill-down of NAKB's content.
核酸知识库(nakb.org)是一个新的数据资源,每周更新,包含实验确定的含有 DNA 和/或 RNA 核酸聚合物及其生物组装体的 3D 结构。NAKB 索引来源于所有主要结构测定方法(X 射线、NMR 和 EM)的含核酸结构,包括蛋白质数据库(PDB)中保存的所有结构。作为核酸数据库(NDB)的计划继任者,NAKB 的设计保留了 NDB 的所有功能,并提供了新的以核酸为中心的内容,包括结构和功能注释,以及来自和链接到外部资源的注释。开发了各种定制的交互工具,以实现对 NAKB 内容的快速探索和深入研究。