Environmental Engineering Division, Department of Civil Engineering, Indian Institute of Technology Kharagpur, Kharagpur 721302, India.
Department of Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur 721302, India.
Bioresour Technol. 2024 Jan;392:129998. doi: 10.1016/j.biortech.2023.129998. Epub 2023 Nov 11.
The effects of sulfamethoxazole (SMZ), an antibiotic commonly detected in the water environment, on the performance of a single staged anoxic/oxic moving bed biofilm reactor (A/O MBBR), was investigated. The anoxic zone played a key role in the removal of SMZ with a percentage of contribution accounting for around 85% in the overall removal. Denitrifying heterotrophic microbes present in the anoxic zone showed relatively more resistance to higher SMZ loads. It was found that in extracellular polymeric substances, protein content was increased consistently with the increase in SMZ concentration. Based on the detected biotransformation products, four degradation pathways were proposed and the toxicity was evaluated. Metagenomic analysis revealed that at higher SMZ load the activity of genera, such as Proteobacteria and Actinobacteria was significantly affected. In summary, proper design and operation of staged A/O MBBR can offer a resilient and robust treatment towards SMZ removal from wastewater.
研究了环境中常见抗生素磺胺甲恶唑 (SMZ) 对单级缺氧/好氧移动床生物膜反应器 (A/O MBBR) 性能的影响。缺氧区在 SMZ 的去除中起着关键作用，其在总去除中约占 85%的贡献。缺氧区存在的异养反硝化微生物对较高的 SMZ 负荷表现出相对更高的抗性。结果发现，在胞外聚合物中，蛋白质含量随着 SMZ 浓度的增加而持续增加。根据检测到的生物转化产物，提出了四种降解途径并进行了毒性评估。宏基因组分析表明，在较高的 SMZ 负荷下，变形菌门和放线菌门等属的活性受到显著影响。综上所述，适当设计和操作分阶段 A/O MBBR 可以为从废水中去除 SMZ 提供有弹性和强大的处理方法。
