Department of Critical Care Medicine, Affiliated Hospital of Zunyi Medical University, Dalian road 149, Zunyi city, Guizhou province, China.
Department of Pathology, Affiliated Hospital of Zunyi Medical University, Zunyi city, Guizhou province, China.
BMC Infect Dis. 2023 Nov 14;23(1):792. doi: 10.1186/s12879-023-08790-z.
Cancer case during pregnancy is rare, but it is the second leading cause of maternal mortality.
A-32-year old pregnant woman with a gestational age of 37 weeks was admitted to the hospital due to repeated coughing for 5 months. She received Veno-Venous Extracorporeal Membrane Oxygenation (V-V ECMO) treatment for severe hypoxemia after delivery. She was diagnosed with non-small cell lung cancer (NSCLC) with bone metastasis and pneumocystis pneumonia (PCP). She subsequently received anti-tumor therapy and anti-infective therapy. After treatment, her condition improved and she was weaned from ECMO. Two weeks after weaning ECMO, her condition worsened again. Her family chose palliative treatment, and she ultimately died.
NSCLC is rare during pregnancy. At present, there is still a lack of standardized methods to manage these cases. For theses cases, the clinician should be wary of opportunistic infections, such as pneumocystis jirovecii (P. jirovecii) and Elizabethkingia spp. Specialized medical teams with abundant experience and multidisciplinary discussions from the perspectives of the patient's clinical characteristics as well as preferences are crucial for developing individualized and the best approach.
妊娠期癌症较为罕见，但它是导致产妇死亡的第二大原因。
一位 32 岁的孕妇，妊娠 37 周，因反复咳嗽 5 个月入院。她在分娩后因严重低氧血症接受了静脉-静脉体外膜肺氧合（V-V ECMO）治疗。她被诊断患有非小细胞肺癌（NSCLC）伴骨转移和肺孢子菌肺炎（PCP）。随后，她接受了抗肿瘤治疗和抗感染治疗。治疗后，她的病情有所改善，并成功撤离 ECMO。撤离 ECMO 两周后，她的病情再次恶化。她的家人选择了姑息治疗，最终她去世了。
妊娠期非小细胞肺癌较为罕见。目前，对于此类病例仍缺乏标准化的处理方法。对于这些病例，临床医生应警惕机会性感染，如肺孢子菌（P. jirovecii）和伊丽莎白菌属（Elizabethkingia spp.）。拥有丰富经验的专业医疗团队，以及从患者临床特征和偏好角度出发的多学科讨论，对于制定个体化和最佳治疗方案至关重要。
