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癌症与妊娠:综述

Cancer and Pregnancy: A Comprehensive Review.

作者信息

Schwab Roxana, Anic Katharina, Hasenburg Annette

机构信息

Department of Obstetrics and Women's Health, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.

出版信息

Cancers (Basel). 2021 Jun 18;13(12):3048. doi: 10.3390/cancers13123048.

DOI:10.3390/cancers13123048
PMID:34207252
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8234287/
Abstract

Cancer diagnosis and treatment in pregnant women is a challenging situation. A multidisciplinary network of specialists is required to guide both, the expecting mother and the unborn child through the diagnostic workup and the cytotoxic therapy, by balancing the respective risks and benefits. Tumor entity, stage, biology and gestational week at diagnosis determine the appropriate approach. As premature delivery emerged as one of the main risk factors for adverse long-term outcome of the progeny, it should be avoided, if reasonable from the oncological perspective. This article offers a comprehensive review with respect to the various aspects of cancer in pregnancy.

摘要

孕妇的癌症诊断与治疗是一种具有挑战性的情况。需要一个多学科专家网络,通过平衡各自的风险和益处,指导准妈妈和未出生的胎儿完成诊断检查和细胞毒性治疗。肿瘤的实体、分期、生物学特性以及诊断时的孕周决定了合适的治疗方法。由于早产已成为后代长期不良结局的主要风险因素之一,如果从肿瘤学角度来看合理,就应避免早产。本文就妊娠期间癌症的各个方面提供了全面的综述。

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本文引用的文献

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Approaches to the Diagnosis and Management of Ovarian Cancer in Pregnancy.妊娠期卵巢癌的诊断与管理方法
Cancer Manag Res. 2021 Mar 11;13:2329-2339. doi: 10.2147/CMAR.S290592. eCollection 2021.
2
Fertility-Sparing Surgery in Gynecologic Cancer: A Systematic Review.妇科癌症保留生育功能手术:一项系统评价
Cancers (Basel). 2021 Feb 28;13(5):1008. doi: 10.3390/cancers13051008.
3
Oncologic outcomes of uterine preservation for pre-menopausal patients with stage II epithelial ovarian carcinoma.绝经前 II 期上皮性卵巢癌患者保留子宫的肿瘤学结局。
Int J Gynecol Cancer. 2021 Mar;31(3):480-483. doi: 10.1136/ijgc-2020-001747.
4
Conization and lymph node evaluation as a fertility-sparing treatment for early stage cervical cancer.锥形切除术和淋巴结评估作为早期宫颈癌的保留生育力治疗。
Int J Gynecol Cancer. 2021 Mar;31(3):457-461. doi: 10.1136/ijgc-2020-001740.
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Oncologic and obstetric outcomes after simple conization for fertility-sparing surgery in FIGO 2018 stage IB1 cervical cancer.2018 年FIGO 分期 IB1 期宫颈癌行保留生育功能的单纯宫颈锥切术后的肿瘤学和产科结局。
Int J Gynecol Cancer. 2021 Mar;31(3):452-456. doi: 10.1136/ijgc-2020-001750.
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Imaging modalities in pregnant cancer patients.孕妇癌症患者的影像学检查方法。
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