Schwab Roxana, Anic Katharina, Hasenburg Annette
Department of Obstetrics and Women's Health, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Cancers (Basel). 2021 Jun 18;13(12):3048. doi: 10.3390/cancers13123048.
Cancer diagnosis and treatment in pregnant women is a challenging situation. A multidisciplinary network of specialists is required to guide both, the expecting mother and the unborn child through the diagnostic workup and the cytotoxic therapy, by balancing the respective risks and benefits. Tumor entity, stage, biology and gestational week at diagnosis determine the appropriate approach. As premature delivery emerged as one of the main risk factors for adverse long-term outcome of the progeny, it should be avoided, if reasonable from the oncological perspective. This article offers a comprehensive review with respect to the various aspects of cancer in pregnancy.
孕妇的癌症诊断与治疗是一种具有挑战性的情况。需要一个多学科专家网络,通过平衡各自的风险和益处,指导准妈妈和未出生的胎儿完成诊断检查和细胞毒性治疗。肿瘤的实体、分期、生物学特性以及诊断时的孕周决定了合适的治疗方法。由于早产已成为后代长期不良结局的主要风险因素之一,如果从肿瘤学角度来看合理,就应避免早产。本文就妊娠期间癌症的各个方面提供了全面的综述。