School of Nursing, Army Medical University, Chongqing, People's Republic of China.
Nursing Department, Qionglai Medical Center Hospital, Qionglai, Chengdu, People's Republic of China.
Int J Chron Obstruct Pulmon Dis. 2023 Nov 9;18:2497-2508. doi: 10.2147/COPD.S434743. eCollection 2023.
The rural-urban gap in sociodemographic, lifestyle, and disease-related characteristics among COPD patients is prevalent. These differences may influence the prevalence of mild cognitive impairment (MCI). This study aimed to compare the prevalence and determinants of MCI between rural and urban areas among COPD patients.
The cross-sectional study sample comprised 372 COPD patients from China. We evaluated the cognitive function and lung function, collected sociodemographic, lifestyle, and disease-related information, to compare the prevalence of MCI in rural and urban areas. Using multivariate regression analysis to examine the effects of variables to MCI.
The prevalence of MCI in rural areas was higher than that in urban areas (65.4% vs 47.9%, P=0.001). The prevalence in farm laborers was almost twice as high as that of non-farm laborers in urban areas (82.6% vs 43.1%), but no significant difference in rural areas (P=0.066). However, the data were lower in subjects who insisted on long-term home oxygen therapy (39.7%, CI:27.8-51.6, P<0.001), and who with higher monthly household income (49.6%, CI:40.2-58.9) in rural areas, but no significant difference in urban areas (P=0.985 and 0.502). Multivariate logistic regression analysis indicated that participants aged 71 years and above, former smokers were at a high risk of MCI in both urban and rural areas. However, participants who slept for 6-8 hours a day, shopping frequently, or exercised for more than 2 hours a day had a lower risk of MCI in urban areas. But rural participants who insisted on long-term home oxygen therapy had a lower probability of developing MCI.
This study revealed that there were significant differences in MCI among COPD patients in rural and urban areas, especially in exercise, sleeping, shopping, and long-term home oxygen therapy. Medical staff should give health guidance according to the actual situation of patients with COPD.
农村和城市地区 COPD 患者在社会人口统计学、生活方式和与疾病相关的特征方面存在城乡差距。这些差异可能会影响轻度认知障碍（MCI）的患病率。本研究旨在比较农村和城市地区 COPD 患者中 MCI 的患病率及其决定因素。
这项横断面研究的样本包括来自中国的 372 名 COPD 患者。我们评估了认知功能和肺功能，收集了社会人口统计学、生活方式和与疾病相关的信息，以比较农村和城市地区 MCI 的患病率。使用多变量回归分析来检查变量对 MCI 的影响。
农村地区 MCI 的患病率高于城市地区（65.4%对 47.9%，P=0.001）。农村地区农民的患病率几乎是城市地区非农民的两倍（82.6%对 43.1%），但农村地区没有显著差异（P=0.066）。然而，在坚持长期家庭氧疗的患者中（39.7%，CI：27.8-51.6，P<0.001）和家庭月收入较高的患者中（49.6%，CI：40.2-58.9），农村地区的数据较低，但在城市地区没有显著差异（P=0.985 和 0.502）。多变量逻辑回归分析表明，农村和城市地区年龄在 71 岁及以上、曾吸烟的参与者患 MCI 的风险较高。然而，每天睡眠 6-8 小时、经常购物或每天运动超过 2 小时的参与者，患 MCI 的风险较低。但农村地区坚持长期家庭氧疗的患者发生 MCI 的可能性较低。
本研究表明，农村和城市地区 COPD 患者的 MCI 存在显著差异，特别是在运动、睡眠、购物和长期家庭氧疗方面。医务人员应根据 COPD 患者的实际情况给予健康指导。
