Yu Jingwei, Fu Yanhong, Zeng Lei, Xie Pengpeng, Li Limei, Zheng Yongxia
<institution content-type="university">Gynecology of Traditional Chinese Medicine, Panyu Maternal and Child Care Service Centre (Panyu He Xian Memorial Hospital)</institution>, <city>Guangzhou City</city>, <state>Guangdong Province</state> <postal-code>511442</postal-code>, <country>China</country>.
<institution content-type="university">Department of Gynecology, Guangzhou Huadu District Maternal and Child Care Service Centre</institution>, <city>Guangzhou City</city>, <state>Guangdong Province</state> <postal-code>510800</postal-code>, <country>China</country>.
Sex Health. 2023 Dec;20(6):577-584. doi: 10.1071/SH23029.
Infertility is a common reproductive disease that affects not only individuals and families, but also the growth of the social population. Hence, understanding the burden of female infertility in China and worldwide is of great significance for the development of infertility prevention and treatment strategies.
The Global Burden of Disease Study (GBD 2019) Data Resources were used to collect and collate relevant data on female infertility in China and worldwide from 1990 to 2019. The difference in the number, age-standardised prevalence rate (ASPR), disability-adjusted life years and age-standardised disability-adjusted life years rate (ASDR) of women with infertility in different periods and geographical areas were analysed. The autoregressive integrated moving average method was used to predict the ASPR and ASDR of female infertility in China and worldwide in the next 11years.
In the past 30years, the number of female infertility cases increased by 7.06million in China and 56.71million worldwide. The corresponding average annual increase of ASPR was 10.10% and 7.28%, respectively, and that of ASDR was 0.08% and 0.79%, respectively. In addition, there are differences in age and time between Chinese and global female infertility. In 1990, the crude prevalence rate of female infertility was the highest in women aged 40-44years and 35-39years in China and worldwide, respectively. In 2019, the crude prevalence rate of female infertility was still the highest in women aged 40-44years in China, whereas that around the world reached the highest in women aged 30-34years, which was significantly earlier. The forecast for the next 11years suggests that the ASPR and ASDR for female infertility in China will first rise and then decline, but the overall magnitude of change is not very significant, whereas the ASPR and ASDR for female infertility globally are still on the rise. The ASPR value of female infertility is expected to be 5025.56 in 100 000 persons in China and 3725.51 in 100 000 persons worldwide by 2030. The ASDR value of female infertility is expected to be 26.16 in 100 000 persons in China and 19.96 in 100 000 persons worldwide by 2030.
The burden of female infertility is still increasing in China and worldwide. Therefore, it is of great significance to pay more attention to infertile women, and advocate a healthy lifestyle to reduce the burden of disease for infertile women.
不孕症是一种常见的生殖疾病，不仅影响个人和家庭，还影响社会人口的增长。因此，了解中国和全球女性不孕症的负担对于制定不孕症防治策略具有重要意义。
利用全球疾病负担研究（GBD 2019）数据资源，收集并整理1990年至2019年中国和全球女性不孕症的相关数据。分析不同时期和地理区域不孕症女性的数量、年龄标准化患病率（ASPR）、伤残调整生命年和年龄标准化伤残调整生命年率（ASDR）的差异。采用自回归积分滑动平均法预测未来11年中国和全球女性不孕症的ASPR和ASDR。
在过去30年中，中国女性不孕症病例数增加了706万，全球增加了5671万。相应的ASPR年均增长率分别为10.10%和7.28%，ASDR年均增长率分别为0.08%和0.79%。此外，中国和全球女性不孕症在年龄和时间上存在差异。1990年，中国40-44岁女性和全球35-39岁女性的不孕症粗患病率最高。2019年，中国40-44岁女性的不孕症粗患病率仍然最高，而全球30-34岁女性的不孕症粗患病率最高，且时间明显提前。未来11年的预测表明，中国女性不孕症的ASPR和ASDR将先上升后下降，但总体变化幅度不大，而全球女性不孕症的ASPR和ASDR仍在上升。预计到2030年，中国女性不孕症的ASPR值将达到每10万人5025.56例，全球将达到每10万人3725.51例。预计到2030年，中国女性不孕症的ASDR值将达到每10万人26.16例，全球将达到每10万人19.96例。
中国和全球女性不孕症的负担仍在增加。因此，更加关注不孕女性，倡导健康的生活方式以减轻不孕女性的疾病负担具有重要意义。
