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印度迈索尔农村青春期女学生的维生素B12状况:一项基于社区的横断面研究。

Vitamin B12 Status in Rural Adolescent School Girls in Mysuru, India: A Community-Based Cross-Sectional Study.

作者信息

Kumar K Jagadish, Balaji Sangeetha, Kulkarni Praveen, Manjunath V G, Nandish H R

机构信息

Pediatrics, JSS Medical College, JSS Academy of Higher Education and Research, Mysore, Karnataka, India.

Community Medicine, JSS Medical College, JSS Academy of Higher Education and Research, Mysore, Karnataka, India.

出版信息

Indian J Community Med. 2023 Sep-Oct;48(5):794-797. doi: 10.4103/ijcm.ijcm_863_22. Epub 2023 Sep 7.

DOI:10.4103/ijcm.ijcm_863_22
PMID:37970155
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10637595/
Abstract

Almost 56% of Indian adolescent girls aged 15-19 years suffer from anemia. Adolescent age is a period of many significant physiological changes that increase nutritional demand, and they remain at risk for nutritional deficiencies. Our aim is to assess the prevalence of Vitamin B12 deficiency among school-going adolescent girls aged 13-16 years of rural Mysore. This study was a cross-sectional study, conducted in two high schools in rural Mysuru. Adolescent girls aged 13-16 years were included. The chosen subjects underwent complete hemogram, peripheral smear examination, and vitamin B12 level estimation. Out of 98 subjects enrolled, 40.81% were found to be deficient in vitamin B12. Macrocytes and hyper-segmented neutrophils were found to have statistically significant ( value < 0.001) relationship with vitamin B12 deficiency. The relationship between vitamin B12 deficiency with either type of diet and anemia was statically insignificant ( > 0.05). The prevalence of vitamin B12 deficiency among rural adolescent girls in Mysuru is high. Other causes of nutritional anemia apart from iron deficiency, such as vitamin B12 deficiency, must be considered in the etiology of anemia and optimally treated. It is recommended to further strengthen the adolescent national health programs and food fortification programs.

摘要

近56%的15至19岁印度少女患有贫血症。青春期是许多重大生理变化的时期,这会增加营养需求,她们仍面临营养缺乏的风险。我们的目的是评估迈索尔农村地区13至16岁在校青春期女孩中维生素B12缺乏症的患病率。本研究是一项横断面研究,在迈索尔农村的两所高中进行。纳入了13至16岁的青春期女孩。选定的受试者进行了全血细胞计数、外周血涂片检查和维生素B12水平测定。在98名登记的受试者中,发现40.81%的人维生素B12缺乏。发现巨红细胞和多分叶中性粒细胞与维生素B12缺乏有统计学显著关系(值<0.001)。维生素B12缺乏与任何一种饮食类型和贫血之间的关系在统计学上不显著(>0.05)。迈索尔农村青春期女孩中维生素B12缺乏症的患病率很高。在贫血的病因中,除了缺铁之外,其他营养性贫血的原因,如维生素B12缺乏,也必须加以考虑并进行最佳治疗。建议进一步加强青少年国家健康计划和食品强化计划。

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本文引用的文献

1
The prevalence of low serum levels of Vitamin D, Vitamin B12, folate and ferritin in adolescents: Single center experience.青少年血清维生素 D、维生素 B12、叶酸和铁蛋白水平低的患病率:单中心经验。
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Prevalence of vitamin B deficiency in healthy Indian school-going adolescents from rural and urban localities and its relationship with various anthropometric indices: a cross-sectional study.维生素 B 缺乏症在农村和城市地区健康印度在校青少年中的流行情况及其与各种人体测量指数的关系:一项横断面研究。
J Hum Nutr Diet. 2018 Aug;31(4):513-522. doi: 10.1111/jhn.12541. Epub 2018 Feb 22.
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Folate and vitamin B12 status and dietary intake of anaemic adolescent schoolgirls in the delta region of Myanmar.缅甸三角洲地区贫血青春期女学生的叶酸、维生素B12状况及饮食摄入情况
Br J Nutr. 2016 Jul;116 Suppl 1:S36-41. doi: 10.1017/S0007114515001609. Epub 2015 Oct 20.
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Vitamin B12 deficiency - A 21st century perspective .维生素B12缺乏症——21世纪视角
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6
Prevalence of Folate, Ferritin and Cobalamin Deficiencies amongst Adolescent in India.印度青少年中叶酸、铁蛋白和钴胺素缺乏症的患病率
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The prevalence of cobalamin deficiency among vegetarians assessed by serum vitamin B12: a review of literature.血清维生素 B12 评估素食者钴胺素缺乏症的流行情况:文献综述。
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