Department of Pediatrics, Gazi University Faculty of Medicine, Ankara, Turkiye.
Sci Prog. 2021 Apr-Jun;104(2):368504211007667. doi: 10.1177/00368504211007667.
In this study, the aim was to evaluate the prevalence of vitamin D, vitamin B12, ferritin, and folate deficiencies in adolescence to clarify the need for early diagnosis and therapy.
The medical records of adolescents between 10 and 18 years of age between 01 September 2018 and 28 February 2019 as healthy with non-specific complaints, or due to well-child care visits, were analyzed retrospectively.
A total of 1847/2507 (73.6%) adolescents were included in the study. The prevalence of vitamin D deficiency was 25.7% (n: 178/691). Vitamin B12 deficiency prevalence was 69.2% (n: 753/1088). The prevalence of anemia and ferritin deficiency was 4.8% and 13.26%. The prevalence of folate deficiency was 37.9% (n: 413/1088). VDD prevalence was statistically significantly higher in females than males (F/M:116/62). VB12D prevalence, the number and mean age of females with hemoglobin deficiency, and low ferritin levels was found to be statistically significantly higher in females than males.
The prevalence of vitamin D, vitamin B12, folate deficiency and low ferritin levels was found to be high among adolescents. In particular, adolescents admitting with non-specific complaints and for control purposes in big cities must be considered to be at risk for the deficiency of these vitamins and low level of ferritin.
本研究旨在评估青少年维生素 D、维生素 B12、铁蛋白和叶酸缺乏症的流行情况，以明确早期诊断和治疗的必要性。
回顾性分析了 2018 年 9 月 1 日至 2019 年 2 月 28 日期间因非特异性症状或常规健康检查而就诊的 10 至 18 岁青少年的病历。
共有 1847/2507（73.6%）名青少年纳入本研究。维生素 D 缺乏症的患病率为 25.7%（n：178/691）。维生素 B12 缺乏症的患病率为 69.2%（n：753/1088）。贫血和铁蛋白缺乏症的患病率分别为 4.8%和 13.26%。叶酸缺乏症的患病率为 37.9%（n：413/1088）。女性的 VDD 患病率明显高于男性（F/M：116/62）。VB12D 的患病率、血红蛋白缺乏症女性的数量和平均年龄以及低铁蛋白水平均明显高于男性。
青少年维生素 D、维生素 B12、叶酸缺乏症和低铁蛋白水平的患病率较高。特别是在大城市因非特异性症状就诊和接受常规检查的青少年，必须考虑存在这些维生素缺乏症和低铁蛋白水平的风险。
