College of Horticulture and Gardening, Yangtze University, Jingzhou, 434025, Hubei, China.
Planta. 2023 Nov 16;259(1):2. doi: 10.1007/s00425-023-04268-z.
This review summarized how TFs function independently or in response to environmental factors to regulate terpenoid biosynthesis via fine-tuning the expression of rate-limiting enzymes. Terpenoids are derived from various species and sources. They are essential for interacting with the environment and defense mechanisms, such as antimicrobial, antifungal, antiviral, and antiparasitic properties. Almost all terpenoids have high medicinal value and economic performance. Recently, the control of enzyme genes on terpenoid biosynthesis has received a great deal of attention, but transcriptional factors regulatory network on terpenoid biosynthesis and accumulation has yet to get a thorough review. Transcription factors function as activators or suppressors independently or in response to environmental stimuli, fine-tuning terpenoid accumulation through regulating rate-limiting enzyme expression. This study investigates the advancements in transcription factors related to terpenoid biosynthesis and systematically summarizes previous works on the specific mechanisms of transcription factors that regulate terpenoid biosynthesis via hormone signal-transcription regulatory networks in plants. This will help us to better comprehend the regulatory network of terpenoid biosynthesis and build the groundwork for terpenoid development and effective utilization.
本文综述了转录因子如何通过精细调控限速酶的表达，独立或响应环境因素来调节萜类化合物的生物合成。萜类化合物来源于不同的物种和来源，对于与环境的相互作用和防御机制（如抗菌、抗真菌、抗病毒和抗寄生虫特性）至关重要。几乎所有萜类化合物都具有很高的药用价值和经济性能。最近，对酶基因控制萜类化合物生物合成的研究受到了极大关注，但转录因子对萜类化合物生物合成和积累的调控网络尚未得到全面综述。转录因子作为激活剂或抑制剂，独立或响应环境刺激，通过调节限速酶的表达来精细调控萜类化合物的积累。本研究调查了与萜类化合物生物合成相关的转录因子的最新进展，并系统总结了前人关于转录因子通过植物激素信号-转录调控网络调节萜类化合物生物合成的具体机制的研究工作。这将有助于我们更好地理解萜类化合物生物合成的调控网络，并为萜类化合物的开发和有效利用奠定基础。
