Suppr超能文献

中耳类癌肿瘤:诊断难题

Middle Ear Carcinoid Tumour a Diagnostic Dilemma.

作者信息

Nabeel M, Reddy Birudavolu Vikyath, Sushmitha P, Sathish Kumar S

机构信息

Department of ENT, Vydehi Institute of Medical Sciences and Research Centre (VIMS&RC), Bangalore, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2023 Dec;75(4):4079-4082. doi: 10.1007/s12070-023-04035-2. Epub 2023 Jul 14.

Abstract

Carcinoid tumours are neuroendocrine tumours associated with gastrointestinal tract, lungs and rarely seen in middle ear. A 29 year old male presented with nonspecific symptoms of blocking sensation, reduced hearing and tinnitus in the right ear. Otoscopy showed congestion of right tympanic membrane with bulge in anterior quadrant with no blanching on siegalization. Audiometry showing conductive hearing loss. CT scan showing mildly enhancing mass in the right middle ear cavity. Complete excision was done and Histopathological studied showed features favouring adenoma and immunohistochemistry showed positive staining of Pan Cytokeratin, Synaptophysis and Chromogranin A, with Ki-67 01% suggestive of carcinoid tumour. Patient underwent PET Scaning post operatively to rule out carcinoid tumour elsewhere in the body. Patient is on follow-up every month to look for any recurrence.

摘要

类癌肿瘤是与胃肠道、肺部相关的神经内分泌肿瘤,很少见于中耳。一名29岁男性出现右耳堵塞感、听力下降和耳鸣等非特异性症状。耳镜检查显示右鼓膜充血,前象限膨出,Siegalization试验无苍白。听力测定显示传导性听力损失。CT扫描显示右中耳腔内有轻度强化肿块。进行了完整切除,组织病理学研究显示具有腺瘤特征,免疫组织化学显示全细胞角蛋白、突触素和嗜铬粒蛋白A呈阳性染色,Ki-67为01%,提示为类癌肿瘤。患者术后接受PET扫描以排除身体其他部位的类癌肿瘤。患者每月接受随访以寻找任何复发情况。

相似文献

1
Middle Ear Carcinoid Tumour a Diagnostic Dilemma.中耳类癌肿瘤:诊断难题
Indian J Otolaryngol Head Neck Surg. 2023 Dec;75(4):4079-4082. doi: 10.1007/s12070-023-04035-2. Epub 2023 Jul 14.
3
A case of carcinoid tumor of the middle ear.一例中耳类癌肿瘤病例。
Auris Nasus Larynx. 2003 Feb;30 Suppl:S99-102. doi: 10.1016/s0385-8146(02)00126-8.
4
[Middle ear adenoma/middle ear carcinoid--an unproblematic tumor?].[中耳腺瘤/中耳类癌——一种无问题的肿瘤?]
Laryngorhinootologie. 2009 Mar;88(3):186-90. doi: 10.1055/s-0028-1102933. Epub 2008 Dec 8.
5
Ceruminous Adenoma: A Rare Mass that Impair Hearing.耵聍腺瘤:一种影响听力的罕见肿物。
Medeni Med J. 2021;36(3):270-275. doi: 10.5222/MMJ.2021.36974. Epub 2021 Sep 30.
6
Middle Ear Neuroendocrine Tumor Mimicking As Chronic Otitis Media.酷似慢性中耳炎的中耳神经内分泌肿瘤
Cureus. 2023 Jul 22;15(7):e42296. doi: 10.7759/cureus.42296. eCollection 2023 Jul.
8
Carcinoid tumor of the middle ear.中耳类癌肿瘤。
J Med Assoc Thai. 2007 Apr;90(4):805-8.

本文引用的文献

1
Primary Carcinoid Tumor of the Testis: Case Report.睾丸原发性类癌肿瘤:病例报告
Urol Case Rep. 2015 Jun 10;3(5):152-4. doi: 10.1016/j.eucr.2015.05.003. eCollection 2015 Sep.
2
Carcinoid tumor of the middle ear: report of a case.中耳类癌肿瘤:一例报告
Am J Otolaryngol. 2008 Sep-Oct;29(5):352-6. doi: 10.1016/j.amjoto.2007.09.008. Epub 2008 Jun 13.
3
Carcinoid tumor of the middle ear.
Acta Otolaryngol. 2004 Aug;124(6):754-7. doi: 10.1080/00016480410016612.
5
A case of carcinoid tumor of the middle ear.一例中耳类癌肿瘤病例。
Auris Nasus Larynx. 2003 Feb;30 Suppl:S99-102. doi: 10.1016/s0385-8146(02)00126-8.
8
Carcinoid tumor of the middle ear.中耳类癌肿瘤。
Am J Clin Pathol. 1980 Jun;73(6):816-23. doi: 10.1093/ajcp/73.6.816.
9
Carcinoid tumors of the middle ear.中耳类癌肿瘤。
Ann Otol Rhinol Laryngol. 1990 Jul;99(7 Pt 1):547-52. doi: 10.1177/000348949009900710.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验