Nabeel M, Reddy Birudavolu Vikyath, Sushmitha P, Sathish Kumar S
Department of ENT, Vydehi Institute of Medical Sciences and Research Centre (VIMS&RC), Bangalore, India.
Indian J Otolaryngol Head Neck Surg. 2023 Dec;75(4):4079-4082. doi: 10.1007/s12070-023-04035-2. Epub 2023 Jul 14.
Carcinoid tumours are neuroendocrine tumours associated with gastrointestinal tract, lungs and rarely seen in middle ear. A 29 year old male presented with nonspecific symptoms of blocking sensation, reduced hearing and tinnitus in the right ear. Otoscopy showed congestion of right tympanic membrane with bulge in anterior quadrant with no blanching on siegalization. Audiometry showing conductive hearing loss. CT scan showing mildly enhancing mass in the right middle ear cavity. Complete excision was done and Histopathological studied showed features favouring adenoma and immunohistochemistry showed positive staining of Pan Cytokeratin, Synaptophysis and Chromogranin A, with Ki-67 01% suggestive of carcinoid tumour. Patient underwent PET Scaning post operatively to rule out carcinoid tumour elsewhere in the body. Patient is on follow-up every month to look for any recurrence.
类癌肿瘤是与胃肠道、肺部相关的神经内分泌肿瘤,很少见于中耳。一名29岁男性出现右耳堵塞感、听力下降和耳鸣等非特异性症状。耳镜检查显示右鼓膜充血,前象限膨出,Siegalization试验无苍白。听力测定显示传导性听力损失。CT扫描显示右中耳腔内有轻度强化肿块。进行了完整切除,组织病理学研究显示具有腺瘤特征,免疫组织化学显示全细胞角蛋白、突触素和嗜铬粒蛋白A呈阳性染色,Ki-67为01%,提示为类癌肿瘤。患者术后接受PET扫描以排除身体其他部位的类癌肿瘤。患者每月接受随访以寻找任何复发情况。