Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical, Tehran, Iran.
Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, P. O. Box: 14155-6446, Tehran, Iran.
Arch Osteoporos. 2023 Nov 17;18(1):137. doi: 10.1007/s11657-023-01340-9.
Osteosarcopenic obesity is a new syndrome that has been recently discussed in the scientific community. It is a condition that affects the elderly and involves the loss of bone, muscle, and fat tissue. The few studies that have been done on this disease showed that it has a high prevalence among the elderly and can cause various complications. This study was the first one to investigate this syndrome in Iran, and found that its prevalence was 19.83%.
Osteosarcopenic obesity syndrome (OSO) is a condition that involves osteopenia/osteoporosis, sarcopenia, and obesity. It leads to a reduction in the quality of life of the elderly and an increase in hospitalization which has attracted the attention of physicians. This study aimed to determine the prevalence and risk factors of osteosarcopenic obesity in people over 60 years of age in Bushehr.
We used data from the Bushehr study, which included 2426 participants aged ≥ 60 years. We assessed osteoporosis/osteopenia based on T-score; sarcopenia based on hand grip strength, skeletal muscle mass index (SMI), and walking speed; and obesity based on fat mass and BMI for diagnosing OSO. We first examined the factors related to OSO in the univariable analysis and then fitted the multiple logistic regression model, separately for women and men. The result was summarized as adjusted odds ratios with a 95% confidence interval.
In total, 2339 elderly were examined in our study, of which 464 elderly were suffering from osteosarcopenic obesity. The standardized prevalence of OSO was 23.66% (95% CI: 21.15-26.16) in women and 18.53% (95% CI 16.35-20.87) in men. Age was positively linked to osteosarcopenic obesity in both genders and so was diabetes in men. However, education, physical activity, and protein intake were negatively linked to osteosarcopenic obesity in both genders, as well as hypertriglyceridemia and hypertension in women.
The prevalence of OSO among men and women of Bushehr city is high and is related to increasing age, low levels of education, physical activity, and protein intake among women and men.
骨肌减少性肥胖综合征（OSO）是一种涉及低骨量/骨质疏松症、肌少症和肥胖的疾病。它降低了老年人的生活质量，增加了住院率，引起了医生的关注。本研究旨在确定 60 岁以上人群中骨肌减少性肥胖的患病率和危险因素。
我们使用了来自布什尔研究的数据，该研究包括 2426 名年龄≥60 岁的参与者。我们根据 T 评分评估骨质疏松/低骨量；根据手握力、骨骼肌质量指数（SMI）和步行速度评估肌少症；根据体脂和 BMI 评估肥胖，以诊断 OSO。我们首先在单变量分析中检查与 OSO 相关的因素，然后分别为女性和男性拟合多因素逻辑回归模型。结果总结为调整后的优势比及其 95%置信区间。
在总共 2339 名老年人中，我们检查了 464 名患有骨肌减少性肥胖的老年人。OSO 的标准化患病率在女性中为 23.66%（95%CI：21.15-26.16），在男性中为 18.53%（95%CI 16.35-20.87）。年龄在两性中与骨肌减少性肥胖呈正相关，男性中糖尿病也是如此。然而，教育、体力活动和蛋白质摄入在两性中与骨肌减少性肥胖呈负相关，女性中还有高甘油三酯血症和高血压。
布什尔市男女的 OSO 患病率较高，与女性和男性的年龄增长、教育程度较低、体力活动和蛋白质摄入减少有关。
