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Bile acid transport by serum lipoproteins in patients with extrahepatic cholestasis.

作者信息

Hedenborg G, Norlander A, Norman A, Svensson A

出版信息

Scand J Clin Lab Invest. 1986 Dec;46(8):745-50. doi: 10.3109/00365518609084046.

DOI:10.3109/00365518609084046
PMID:3797986
Abstract

Individual bile acid conjugates were determined by gas-liquid chromatography in very low density (VLDL), low density (LDL) and high density (HDL) lipoprotein fractions obtained by sequential ultracentrifugation of serum from cholestatic patients. In the lipoproteins were found 16-48% of the serum bile acids. In LDL, the amount found was twice that in VLDL and HDL together. More cholic than chenodeoxycholic acid was detected in the lipoproteins. The occurrence of bile acids in lipoproteins might be of importance for the transport of bile acids from blood to peripheral tissues during cholestasis.

摘要

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