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Detailed high quality surface-based mouse CAD model suitable for electromagnetic simulations.详细的高质量基于表面的鼠标 CAD 模型,适合电磁仿真。
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本文引用的文献

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Activation of MAP2K signaling by genetic engineering or HF-rTMS promotes corticospinal axon sprouting and functional regeneration.通过基因工程或高频重复经颅磁刺激激活丝裂原活化蛋白激酶激酶(MAP2K)信号通路可促进皮质脊髓轴突发芽和功能再生。
Sci Transl Med. 2023 Jan 4;15(677):eabq6885. doi: 10.1126/scitranslmed.abq6885.
2
Compulsive drug-taking is associated with habenula-frontal cortex connectivity.强迫性药物滥用与缰核-前额叶皮层的连接有关。
Proc Natl Acad Sci U S A. 2022 Dec 13;119(50):e2208867119. doi: 10.1073/pnas.2208867119. Epub 2022 Dec 5.
3
Transcranial magnetic stimulation set-up for small animals.用于小动物的经颅磁刺激装置。
Front Neurosci. 2022 Nov 10;16:935268. doi: 10.3389/fnins.2022.935268. eCollection 2022.
4
In vivo direct imaging of neuronal activity at high temporospatial resolution.在体高时间和空间分辨率下对神经元活动的直接成像。
Science. 2022 Oct 14;378(6616):160-168. doi: 10.1126/science.abh4340. Epub 2022 Oct 13.
5
A high-density theta burst paradigm enhances the aftereffects of transcranial magnetic stimulation: Evidence from focal stimulation of rat motor cortex.高密度 theta 爆发范式增强经颅磁刺激的后效:来自大鼠运动皮层局灶刺激的证据。
Brain Stimul. 2022 May-Jun;15(3):833-842. doi: 10.1016/j.brs.2022.05.017. Epub 2022 May 27.
6
Angle-tuned coils: attractive building blocks for TMS with improved depth-spread performance.角度调谐线圈:用于 TMS 的有吸引力的构建块,可提高深度传播性能。
J Neural Eng. 2022 May 4;19(2). doi: 10.1088/1741-2552/ac697c.
7
Medial prefrontal cortex and anteromedial thalamus interaction regulates goal-directed behavior and dopaminergic neuron activity.内侧前额叶皮层和前内侧丘脑的相互作用调节目标导向行为和多巴胺能神经元活动。
Nat Commun. 2022 Mar 16;13(1):1386. doi: 10.1038/s41467-022-28892-7.
8
Design of a head coil for high resolution mouse brain perfusion imaging using magnetic particle imaging.基于磁粒子成像的高分辨率小鼠脑灌注成像头部线圈设计。
Phys Med Biol. 2020 Dec 23;65(23):235007. doi: 10.1088/1361-6560/abc09e.
9
Converging Structural and Functional Evidence for a Rat Salience Network.汇聚的大鼠突显网络的结构和功能证据。
Biol Psychiatry. 2020 Dec 1;88(11):867-878. doi: 10.1016/j.biopsych.2020.06.023. Epub 2020 Jul 2.
10
A software toolkit for TMS electric-field modeling with boundary element fast multipole method: an efficient MATLAB implementation.一款基于边界元快速多极子方法的 TMS 电场建模软件工具包:一种高效的 MATLAB 实现。
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详细的高质量基于表面的鼠标 CAD 模型,适合电磁仿真。

Detailed high quality surface-based mouse CAD model suitable for electromagnetic simulations.

机构信息

ECE, Worcester Polytech. Inst., 100 Institute Rd. Worcester MA 01609-2280, United States of America.

Ansys, Inc., Boston Campus, 400 5th Ave Suite 500, Waltham MA 02451, United States of America.

出版信息

Biomed Phys Eng Express. 2023 Nov 30;10(1). doi: 10.1088/2057-1976/ad0e14.

DOI:10.1088/2057-1976/ad0e14
PMID:37983756
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10785004/
Abstract

Transcranial magnetic stimulation (TMS) studies with small animals can provide useful knowledge of activating regions and mechanisms. Along with this, functional magnetic resonance imaging (fMRI) in mice and rats is increasingly often used to draw important conclusions about brain connectivity and functionality. For cases of both low- and high-frequency TMS studies, a high-quality computational surface-based rodent model may be useful as a tool for performing supporting modeling and optimization tasks. This work presents the development and usage of an accurate CAD model of a mouse that has been optimized for use in computational electromagnetic modeling in any frequency range. It is based on the labeled atlas data of the Digimouse archive. The model includes a relatively accurate four-compartment brain representation (the 'whole brain' according to the original terminology, external cerebrum, cerebellum, and striatum [9]) and contains 21 distinct compartments in total. Four examples of low- and high frequency modeling have been considered to demonstrate the utility and applicability of the model.

摘要

经颅磁刺激(TMS)研究在小动物身上进行,可以提供激活区域和机制的有用知识。与此同时,功能磁共振成像(fMRI)在小鼠和大鼠中的应用也越来越广泛,这为研究大脑连接和功能提供了重要结论。对于低频和高频 TMS 研究,高质量的基于计算的啮齿动物表面模型可能是一种有用的工具,可以用于执行支持建模和优化任务。本工作提出了一种优化用于任何频率范围内计算电磁建模的小鼠精确 CAD 模型的开发和使用。它基于 Digimouse 档案的标记图谱数据。该模型包括一个相对准确的四腔脑表示(根据原始术语,外部大脑、小脑和纹状体[9]的“整个大脑”),总共包含 21 个不同的腔室。考虑了四个低频和高频建模的例子,以展示模型的实用性和适用性。