Zarandi Mohammad Amin, Pathak Pravin, Beltrami Noah, Walker Jada N, Zhang Fengqi, Brodbelt Jennifer S, Schmehl Russell, Jayawickramarajah Janarthanan
Department of Chemistry, Tulane University, New Orleans, LA, 70118, USA.
Department of Chemistry, The University of Texas at Austin, Austin, TX 78712, USA.
Nanoscale. 2023 Dec 7;15(47):19069-19073. doi: 10.1039/d3nr04086k.
A heteromeric guanosine (G)-quadruplex centered self-assembly approach is developed to prepare compact light-harvesting antenna modules featuring multiple donor dyes and a single toehold region. Due to the mix-and-match nature of our approach, the number and placement of donor dyes can be readily fine-tuned quadruplex assembly. Moreover, hybridization of the toehold with an acceptor containing sequence results in directional energy transfer ensembles with effective absorption coefficients in the 10 M cm range. These compact antennas exhibit system efficiencies that are comparable to much larger and elaborate DNA architectures containing numerous DNA strands.
开发了一种以异源三聚体鸟苷（G）-四链体为中心的自组装方法，以制备具有多个供体染料和单个引物区域的紧凑型光捕获天线模块。由于我们方法的混合搭配性质，可以很容易地对四链体组装中供体染料的数量和位置进行微调。此外，引物与含受体序列的杂交产生了具有10 M cm范围内有效吸收系数的定向能量转移组件。这些紧凑型天线表现出的系统效率与包含大量DNA链的大得多且复杂的DNA结构相当。
