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肥胖问题圆桌会议:儿童及青少年的代谢与减重手术

Obesity Pillars roundtable: Metabolic and bariatric surgery in children and adolescents.

作者信息

Cuda Suzanne E, Pratt Janey S A, Santos Melissa, Browne Allen

机构信息

American Board of Obesity Medicine, Alamo City Healthy Kids & Families, 1919 Oakwell Farms Parkway, Suite 145, San Antonio, TX, 78218, USA.

American Society of Metabolic and Bariatric Surgery Committee on Pediatrics, Adolescent Bariatric Surgery, Lucille Packard Children's Hospital, Stanford University School of Medicine, Center for Academic Medicine, 4th Floor Division of Pediatric Surgery, 453 Quarry Rd, Palo Alto, CA, 94304, USA.

出版信息

Obes Pillars. 2022 Jun 8;3:100023. doi: 10.1016/j.obpill.2022.100023. eCollection 2022 Sep.

Abstract

BACKGROUND

Obesity is a chronic disease which frequently begins in childhood and requires a life-long multidisciplinary approach. Metabolic-bariatric surgery (MBS) is a key component of the treatment of severe obesity in children, adolescents and adults. Children and adolescents who have class II obesity and a complication of obesity or have class III obesity should be considered for MBS, regardless of age, race, sex, or gender. Children and adolescents with cognitive disabilities, a history of mental illness, a treated eating disorder, immature bone growth, or low Tanner Stage should not be denied treatment. Early intervention can reduce the risk of persistent obesity, end organ damage, and sequelae from long-standing complications of obesity.

METHODS

This roundtable discussion includes three pediatric obesity specialists with experience in the medical and surgical management of children and adolescents with obesity. Included are citations regarding metabolic-bariatric surgery in children and adolescents.

RESULTS

MBS in pediatric patients is increasingly recognized as an essential part of managing the disease of obesity in combination with medication, nutrition, behavioral training, and physical activity. Vertical sleeve gastrectomy or Roux-en-Y gastric bypass in patients meeting criteria for severe obesity should be considered, especially when children have complications such as poor quality of life, orthopedic disease, idiopathic intracranial hypertension, type 2 diabetes mellitus, obstructive sleep apnea, or cardiovascular risk. Children and adolescents with autism, developmental delay, or syndromic obesity should be considered for MBS on a case-by-case basis. Early intervention may result in improved long-term outcomes, and referral for MBS should not be conditional based on stage of pubertal development (Tanner Staging), bone age, or prior weight loss attempts.

CONCLUSIONS

Children and adolescents who suffer from severe obesity need the entire spectrum of treatment modalities available to achieve a healthy weight and control obesity-related complications. This treatment spectrum should include MBS. These children and adolescents should be cared for by a pediatric weight management team prepared to care for them until they transition to adult care.

摘要

背景

肥胖是一种慢性疾病,通常始于儿童期,需要终身采取多学科方法进行治疗。代谢减重手术(MBS)是治疗儿童、青少年和成人重度肥胖的关键组成部分。患有II类肥胖且伴有肥胖并发症或III类肥胖的儿童和青少年,无论年龄、种族、性别如何,均应考虑进行MBS。患有认知障碍、精神疾病史、已治疗的饮食失调、骨骼生长不成熟或坦纳分期较低的儿童和青少年不应被拒绝治疗。早期干预可降低持续性肥胖、终末器官损害以及肥胖长期并发症后遗症的风险。

方法

本次圆桌讨论包括三位在儿童和青少年肥胖的医学和手术管理方面有经验的儿科肥胖专家。其中包括有关儿童和青少年代谢减重手术的文献引用。

结果

儿科患者的MBS越来越被认为是与药物治疗、营养、行为训练和体育活动相结合管理肥胖疾病的重要组成部分。对于符合重度肥胖标准的患者,应考虑进行垂直袖状胃切除术或Roux-en-Y胃旁路术,尤其是当儿童出现生活质量差、骨科疾病、特发性颅内高压、2型糖尿病、阻塞性睡眠呼吸暂停或心血管风险等并发症时。患有自闭症、发育迟缓或综合征性肥胖的儿童和青少年应根据具体情况考虑进行MBS。早期干预可能会改善长期预后,MBS转诊不应基于青春期发育阶段(坦纳分期)、骨龄或既往减肥尝试情况。

结论

患有重度肥胖的儿童和青少年需要所有可用的治疗方式来实现健康体重并控制肥胖相关并发症。这种治疗范围应包括MBS。这些儿童和青少年应由一个儿科体重管理团队进行护理,该团队应准备好照顾他们,直至他们过渡到成人护理阶段。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b7b/10661994/15b0ae03445c/fx1.jpg

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