Gavrilenkova V Iu, Ulanova A A, Runova V F, Kargina T M, Lapteva L K
Zh Mikrobiol Epidemiol Immunobiol. 1986 Oct(10):65-8.
In vitro experiments have revealed no perceptible decrease in the content of antitoxic antibodies to alphastaphylolysin in the preparations of antistaphylococcal immunoglobulin, containing 13-50% of Fab-fragments. These data confirm the necessity of controlling the molecular composition of the preparations of antistaphylococcal IgG by physico-chemical methods with the aim to evaluate their quality, as the fragmented preparations are rapidly eliminated from a human body.
体外实验表明，在含有13 - 50% Fab片段的抗葡萄球菌免疫球蛋白制剂中，抗α - 葡萄球菌溶血素的抗毒抗体含量没有明显下降。这些数据证实了有必要通过物理化学方法控制抗葡萄球菌IgG制剂的分子组成，以评估其质量，因为片段化制剂会迅速从人体中清除。
