Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.
Laboratory of Cellular and Molecular Gerontology, Precision Nutrition and Aging, IMDEA Food, CEI UAM + CSIC, 028049 Madrid, Spain.
Sci Transl Med. 2023 Nov 22;15(723):eadh1175. doi: 10.1126/scitranslmed.adh1175.
Obesity and aging share comorbidities, phenotypes, and deleterious effects on health that are associated with chronic diseases. However, distinct features set them apart, with underlying biology that should be explored and exploited, especially given the demographic shifts and the obesity epidemic that the world is facing.
肥胖症和衰老存在共病、表型和对健康的有害影响,这些与慢性疾病有关。然而,它们也有明显的区别,其潜在的生物学特性值得我们去探索和利用,尤其是考虑到世界正面临的人口结构变化和肥胖症流行这两大问题。