Division of Pathology, ICAR-Indian Veterinary Research Institute (IVRI), Izatnagar, India.
Division of Pathology, ICAR-Indian Veterinary Research Institute (IVRI), Izatnagar, India; ICAR-DFMD-International Centre for Foot and Mouth Disease, Arugul, Jatni, Bhubaneswar, Odisha.
Vet Ital. 2023 Mar 31;59(1):23-38. doi: 10.12834/VetIt.2935.20591.2.
Porcine Respiratory Disease Complex (PRDC) is an unequivocally leading cause of economic losses to the pig industry. To investigate the pathogens associated with PRDC, a total of 900 lungs with gross lesions and 125 lungs with no appreciable gross lesions were collected from the abattoirs and subjected to pathological investigation for distribution of lesions/and types of exudates, as well as to molecular confirmation of bacterial and viral pathogens by PCR. The pneumonic lungs showed the higher prevalence of Mycoplasma spp. (31.22%), with evidence of M. hyorhinis, P. multocida (21.33%), S. suis (18.66%), B. bronchiseptica (16.77%), and viral pathogens as porcine circovirus type 2 (PCV2) (28.11%), porcine reproductive and respiratory syndrome virus (PRRSV) (2.7%) and swine influenza virus (SIV) (1.2%). On histopathological examination, high prevalence of bronchopneumonia (37.88%) followed by enzootic pneumonia‑like lung lesions (11.44%), and interstitial pneumonia (7.44%) was recorded in the majority of affected pigs. The winter season was found to be more conducive for highest prevalence of pneumonia as compared to other seasons. The present study reports the high prevalence of PRDC in slaughtered pigs of India. M. hyorhinis showing the EP‑like lesions, PCV2 and their combination were likely to be the prime contributors of PRDC in Indian pigs.
猪呼吸道疾病综合征（PRDC）是导致养猪业经济损失的主要原因之一。为了调查与 PRDC 相关的病原体，我们从屠宰场收集了 900 个有明显病变的肺脏和 125 个无明显病变的肺脏，进行了病理学检查，以了解病变分布和渗出物类型，并通过 PCR 对细菌和病毒病原体进行分子确认。肺炎肺脏中支原体属（31.22%）的检出率较高，有猪鼻支原体、多杀性巴氏杆菌（21.33%）、猪链球菌（18.66%）、支气管败血波氏杆菌（16.77%）和病毒病原体，如猪圆环病毒 2 型（PCV2）（28.11%）、猪繁殖与呼吸综合征病毒（PRRSV）（2.7%）和猪流感病毒（SIV）（1.2%）。在组织病理学检查中，大多数受感染猪的支气管肺炎（37.88%）、地方性肺炎样肺病变（11.44%）和间质性肺炎（7.44%）的检出率较高。与其他季节相比，冬季更容易发生肺炎。本研究报告了印度屠宰猪中 PRDC 的高流行率。表现出 EP 样病变的猪鼻支原体、PCV2 及其组合可能是印度猪 PRDC 的主要致病因素。
