Braine Anaelle, Georges François
Univ. Bordeaux, CNRS, IMN, UMR 5293, F-33000 Bordeaux, France.
Univ. Bordeaux, CNRS, IMN, UMR 5293, F-33000 Bordeaux, France.
Neurosci Biobehav Rev. 2023 Dec;155:105475. doi: 10.1016/j.neubiorev.2023.105475. Epub 2023 Nov 22.
The brain is a remarkably complex organ responsible for a wide range of functions, including the modulation of emotional states and movement. Neuronal circuits are believed to play a crucial role in integrating sensory, cognitive, and emotional information to ultimately guide motor behavior. Over the years, numerous studies employing diverse techniques such as electrophysiology, imaging, and optogenetics have revealed a complex network of neural circuits involved in the regulation of emotional or motor processes. Emotions can exert a substantial influence on motor performance, encompassing both everyday activities and pathological conditions. The aim of this review is to explore how emotional states can shape movements by connecting the neural circuits for emotional processing to motor neural circuits. We first provide a comprehensive overview of the impact of different emotional states on motor control in humans and rodents. In line with behavioral studies, we set out to identify emotion-related structures capable of modulating motor output, behaviorally and anatomically. Neuronal circuits involved in emotional processing are extensively connected to the motor system. These circuits can drive emotional behavior, essential for survival, but can also continuously shape ongoing movement. In summary, the investigation of the intricate relationship between emotion and movement offers valuable insights into human behavior, including opportunities to enhance performance, and holds promise for improving mental and physical health. This review integrates findings from multiple scientific approaches, including anatomical tracing, circuit-based dissection, and behavioral studies, conducted in both animal and human subjects. By incorporating these different methodologies, we aim to present a comprehensive overview of the current understanding of the emotional modulation of movement in both physiological and pathological conditions.
大脑是一个极其复杂的器官，负责广泛的功能，包括情绪状态和运动的调节。神经元回路被认为在整合感觉、认知和情绪信息以最终指导运动行为方面起着至关重要的作用。多年来，许多采用电生理学、成像和光遗传学等多种技术的研究揭示了一个参与情绪或运动过程调节的复杂神经回路网络。情绪可对运动表现产生重大影响，涵盖日常活动和病理状况。本综述的目的是探讨情绪状态如何通过将情绪处理的神经回路与运动神经回路相连来塑造运动。我们首先全面概述不同情绪状态对人类和啮齿动物运动控制的影响。与行为研究一致，我们着手从行为和解剖学上识别能够调节运动输出的与情绪相关的结构。参与情绪处理的神经元回路与运动系统广泛相连。这些回路可驱动对生存至关重要的情绪行为，但也能持续塑造正在进行的运动。总之，对情绪与运动之间复杂关系的研究为人类行为提供了有价值的见解，包括提高表现的机会，并有望改善身心健康。本综述整合了在动物和人类受试者中进行的多种科学方法的研究结果，包括解剖追踪、基于回路的剖析和行为研究。通过纳入这些不同的方法，我们旨在全面概述当前对生理和病理状况下运动的情绪调节的理解。
