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音乐疗法增强阿尔茨海默病和混合性痴呆患者的情景记忆:一项双盲随机对照试验。

Music Therapy Enhances Episodic Memory in Alzheimer's and Mixed Dementia: A Double-Blind Randomized Controlled Trial.

作者信息

Moreira Shirlene Vianna, Justi Francis Ricardo Dos Reis, Gomes Carlos Falcão de Azevedo, Moreira Marcos

机构信息

Lato Sensu Postgraduate Program in Psychology, Faculty of Medical and Health Sciences of Juiz de Fora (SUPREMA), Juiz de Fora 36033-003, MG, Brazil.

Department of Psychology, Institute of Human Sciences, Federal University of Juiz de Fora, Juiz de Fora 36036-900, MG, Brazil.

出版信息

Healthcare (Basel). 2023 Nov 7;11(22):2912. doi: 10.3390/healthcare11222912.

DOI:10.3390/healthcare11222912
PMID:37998404
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10671073/
Abstract

: This study aimed to assess whether a music therapy (MT) intervention could improve memory decline in older adults with and without cognitive impairment. A dual-retrieval model of episodic memory was employed to estimate memory processes. : Forty-three older adults with a mean age of 76.49 years ( = 25 with Alzheimer's disease (AD) and mixed dementia, and = 18 healthy older adults) were randomly selected for the experimental and control groups. The study design was a double-blind randomized controlled clinical trial and a certified music therapist delivered the MT. The primary outcomes were measures of working memory, episodic memory, and autobiographical memory. : In the primary outcome measures, MT effects were restricted to episodic memory measures like the Figure Memory Test of the BCSB and the Speech and Sing Memory Test. In both tests, the experimental group improved from pre-test to post-test in delayed recall, but in the Speech and Sing Memory Test, the improvement was restricted to the AD and mixed dementia group. MT had no effects on the secondary outcome measures. : These findings suggest that a structured MT intervention can be promising for rehabilitating episodic memory in older adults with dementia.

摘要

本研究旨在评估音乐疗法(MT)干预能否改善有或无认知障碍的老年人的记忆力衰退。采用情景记忆的双重检索模型来估计记忆过程。43名平均年龄为76.49岁的老年人(25名患有阿尔茨海默病(AD)和混合性痴呆,18名健康老年人)被随机分为实验组和对照组。该研究设计为双盲随机对照临床试验,由一名认证音乐治疗师实施音乐疗法。主要结局指标为工作记忆、情景记忆和自传体记忆的测量。在主要结局指标中,音乐疗法的效果仅限于情景记忆测量,如BCSB的图形记忆测试和言语与歌唱记忆测试。在这两项测试中,实验组在延迟回忆方面从预测试到后测试都有改善,但在言语与歌唱记忆测试中,改善仅限于AD和混合性痴呆组。音乐疗法对次要结局指标没有影响。这些发现表明,结构化的音乐疗法干预对于痴呆老年人情景记忆的康复可能是有前景的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3aa/10671073/646bf29cc6f4/healthcare-11-02912-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3aa/10671073/5b6b0bc953a6/healthcare-11-02912-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3aa/10671073/cadb088de075/healthcare-11-02912-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3aa/10671073/646bf29cc6f4/healthcare-11-02912-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3aa/10671073/5b6b0bc953a6/healthcare-11-02912-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3aa/10671073/cadb088de075/healthcare-11-02912-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3aa/10671073/646bf29cc6f4/healthcare-11-02912-g003.jpg

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Effects of Music Therapy on Patients with Dementia-A Systematic Review.音乐疗法对痴呆症患者的影响——一项系统综述
Geriatrics (Basel). 2020 Sep 25;5(4):62. doi: 10.3390/geriatrics5040062.
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Music Therapy in the Treatment of Dementia: A Systematic Review and Meta-Analysis.音乐疗法在痴呆症治疗中的应用:一项系统评价与荟萃分析
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