Halapas Antonios, Koliastasis Leonidas, Doundoulakis Ioannis, Antoniou Christos-Konstantinos, Stefanadis Christodoulos, Tsiachris Dimitrios
Department of Interventional Cardiologist and THV Program, Athens Medical Center, 11526 Athens, Greece.
Department of Cardiology, Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxelles (ULB), 1000 Brussels, Belgium.
J Cardiovasc Dev Dis. 2023 Nov 19;10(11):469. doi: 10.3390/jcdd10110469.
Transcatheter aortic valve implantation (TAVI) is an established alternative to surgery in patients with symptomatic severe aortic stenosis and has expanded its indications to even low-surgical-risk patients. Conduction abnormalities (CA) and permanent pacemaker (PPM) implantations remain a relatively common finding post TAVI due to the close proximity of the conduction system to the aortic root. New onset left bundle branch block (LBBB) and high-grade atrioventricular block are the most commonly reported CA post TAVI. The overall rate of PPM implantation post TAVI varies and is related to pre- and intra-procedural factors. Therefore, when screening patients for TAVI, Heart Teams should take under consideration the various anatomical, pathophysiological and procedural conditions that predispose to CA and PPM requirement after the procedure. This is particularly important as TAVI is being offered to younger patients with longer life-expectancy. Herein, we highlight the incidence, predictors, impact and management of CA in patients undergoing TAVI.
经导管主动脉瓣植入术(TAVI)是有症状的严重主动脉瓣狭窄患者手术治疗的既定替代方案,其适应证甚至已扩展至手术风险低的患者。由于传导系统与主动脉根部距离较近,传导异常(CA)和永久性起搏器(PPM)植入仍是TAVI术后相对常见的情况。新发左束支传导阻滞(LBBB)和高度房室传导阻滞是TAVI术后最常报告的CA。TAVI术后PPM植入的总体发生率各不相同,且与术前和术中因素有关。因此,在对患者进行TAVI筛查时,心脏团队应考虑到术后易发生CA和需要PPM的各种解剖、病理生理和手术情况。随着TAVI应用于预期寿命更长的年轻患者,这一点尤为重要。在此,我们重点介绍接受TAVI患者中CA的发生率、预测因素、影响及管理。