Ravanbodshirazi Sina, Boutfol Timothée, Safaridehkohneh Neda, Finkler Marc, Mohammadi-Kambs Mina, Ott Albrecht
Biological Experimental Physics, Center for Biophysics, Faculity of Natural Sciences and Technology, Saarland University, Campus B2 1, 66123 Saarbrücken, Germany.
Life (Basel). 2023 Nov 12;13(11):2201. doi: 10.3390/life13112201.
Miller and Urey applied electric sparks to a reducive mixture of CH, NH, and water to obtain a complex organic mixture including biomolecules. In this study, we examined the impact of temperature, initial pressure, ammonia concentration, and the spark generator on the chemical profile of a Miller-Urey-type prebiotic broth. We analyzed the broth composition using Gas Chromatography combined with Mass Spectroscopy (GC/MS). The results point towards strong compositional changes with the nature of the spark. Ammonia exhibited catalytic properties even with non-nitrogen-containing compounds. A more elevated temperature led to a higher variety of substances. We conclude that to reproduce such a broth as well as possible, all the studied parameters need to be tightly controlled, the most difficult and important being spark generation.
米勒和尤里对甲烷、氨气和水的还原性混合物施加电火花，以获得包括生物分子在内的复杂有机混合物。在本研究中，我们考察了温度、初始压力、氨浓度和火花发生器对米勒-尤里型益生元前体肉汤化学组成的影响。我们使用气相色谱结合质谱法（GC/MS）分析肉汤成分。结果表明，火花性质会导致成分发生显著变化。即使对于不含氮的化合物，氨也表现出催化特性。温度升高会导致物质种类增多。我们得出结论，为尽可能重现这样的肉汤，所有研究参数都需要严格控制，其中最困难且最重要的是火花的产生。
