Larit Farida, León Francisco
Laboratoire d'Obtention de Substances Thérapeutiques (LOST), Université Frères Mentouri-Constantine 1, Route de Ain El Bey, Constantine 25017, Algeria.
Department of Drug Discovery and Biomedical Sciences, College of Pharmacy, University of South Carolina, Columbia, SC 29208, USA.
Plants (Basel). 2023 Nov 15;12(22):3860. doi: 10.3390/plants12223860.
Ancient people sought out drugs in nature to prevent, cure, and treat their diseases, including mental illnesses. Plants were their primary source for meeting their healthcare needs. In Algeria, folk medicine remains a fundamental part of the local intangible knowledge. This study aims to conduct a comprehensive ethnomedicinal investigation and documentation of medicinal plants and the different plant formulations traditionally used in Algeria for the treatment of pain, psychiatric, and neurological disorders. It also intends to improve the current knowledge of Algerian folk medicine. Several scientific databases were used to accomplish this work. Based on this investigation, we identified 82 plant species belonging to 69 genera and spanning 38 distinct botanical families used as remedies to treat various psychological and neurological conditions. Their traditional uses and methods of preparation, along with their phytochemical composition, main bioactive constituents, and toxicity were noted. Therefore, this review provides a new resource of information on Algerian medicinal plants used in the treatment and management of neurological and psychological diseases, which can be useful not only for the documentation and conservation of traditional knowledge, but also for conducting future phytochemical and pharmacological studies.
古代人在自然界中寻找药物来预防、治愈和治疗疾病，包括精神疾病。植物是他们满足医疗保健需求的主要来源。在阿尔及利亚，民间医学仍然是当地非物质知识的重要组成部分。本研究旨在对阿尔及利亚传统上用于治疗疼痛、精神和神经疾病的药用植物及不同植物配方进行全面的民族药用调查和记录。它还旨在增进对阿尔及利亚民间医学的现有认识。为完成这项工作使用了几个科学数据库。基于这项调查，我们确定了82种植物，它们属于69个属，分属38个不同的植物科，用作治疗各种心理和神经疾病的药物。记录了它们的传统用途、制备方法以及它们的植物化学成分、主要生物活性成分和毒性。因此，本综述提供了关于用于治疗和管理神经和心理疾病的阿尔及利亚药用植物的新信息资源，这不仅有助于传统知识的记录和保护，也有助于开展未来的植物化学和药理学研究。
