重症肌无力患者的乙酰胆碱受体抗体
Acetylcholine receptor antibody in patients with myasthenia gravis.
作者信息
Xu X H, Zhu L P, Wu J Y, Zhang S Z, Yang G Z, Ba T, Tan M X, Liu S L
出版信息
Asian Pac J Allergy Immunol. 1986 Dec;4(2):101-5.
The determination of acetylcholine receptor antibody (AChR Ab) titer by an enzyme-linked immunosorbent assay (ELISA) in patients with myasthenia gravis was introduced. The optimal conditions were determined by chequerboard determination. The specificity was confirmed by inhibition tests. The sensitivity is 9 p mole. The comparison of AChR Ab titers among 49 myasthenic patients, 19 non-myasthenic neurological patients and 20 healthy blood donors has shown that it is a highly sensitive, specific, reproducible, rapid, simple and inexpensive method for determining AChR Ab and that it is highly valuable for the diagnosis of myasthenia gravis.
介绍了用酶联免疫吸附测定法（ELISA）测定重症肌无力患者乙酰胆碱受体抗体（AChR Ab）滴度。通过棋盘滴定法确定最佳条件。通过抑制试验确认特异性。灵敏度为9皮摩尔。对49例重症肌无力患者、19例非重症肌无力神经系统疾病患者和20名健康献血者的AChR Ab滴度进行比较，结果表明，该方法是一种测定AChR Ab的高灵敏度、特异性、可重复性、快速、简单且廉价的方法，对重症肌无力的诊断具有很高价值。
Zotero 插件