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高地中海饮食依从性与多发性硬化症老年患者残疾和症状严重程度、抑郁、焦虑、压力、睡眠质量、认知障碍和体力活动减少的相关性。

Association of Higher Mediterranean Diet Adherence With Lower Prevalence of Disability and Symptom Severity, Depression, Anxiety, Stress, Sleep Quality, Cognitive Impairment, and Physical Inactivity in Older Adults With Multiple Sclerosis.

机构信息

Department of Food Science and Nutrition, School of Environment, University of the Aegean, Myrina, Greece.

Department of Geriatric Psychiatry, School of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.

出版信息

J Geriatr Psychiatry Neurol. 2024 Jul;37(4):318-331. doi: 10.1177/08919887231218754. Epub 2023 Nov 29.

Abstract

A good nutritional status and healthy diets may decelerate disease disability and symptom severity and quality of life of peoples with multiple sclerosis (MS). Mediterranean diet (MD) can prevent several chronic diseases, including neurodegenerative disease. This is an observational, cross-sectional study on 279 older adults with MS, aiming to investigate the effects of MD against several aspects of mental health. Qualified questionnaires were used to assess disability and symptom severity, depression, anxiety, stress, sleep quality, cognitive status, physical activity, and MD adherence. Multivariate analysis showed that enhanced MD adherence was independently associated with lower prevalence of disability and symptom severity ( = .0019), depression ( = .0201), anxiety ( = .0287), perceived stress ( = .0021), inadequate sleep quality ( = .0033), cognitive impairment ( = .0018) and physical inactivity ( = .0028). Adopting MD may ameliorate mental health disturbances in older adults with MS. Future public health policies should inform older adults with MS for the favorable impacts of MD in improving the mental health MS comorbidities.

摘要

良好的营养状况和健康饮食可能会减缓多发性硬化症(MS)患者的疾病残疾和症状严重程度以及生活质量。地中海饮食(MD)可以预防多种慢性疾病,包括神经退行性疾病。这是一项针对 279 名老年 MS 患者的观察性横断面研究,旨在调查 MD 对心理健康几个方面的影响。合格的问卷用于评估残疾和症状严重程度、抑郁、焦虑、压力、睡眠质量、认知状况、身体活动和 MD 依从性。多变量分析表明,MD 依从性增强与残疾和症状严重程度(=.0019)、抑郁(=.0201)、焦虑(=.0287)、感知压力(=.0021)、睡眠质量差(=.0033)、认知障碍(=.0018)和身体活动不足(=.0028)的患病率降低独立相关。采用 MD 可能会改善老年 MS 患者的心理健康障碍。未来的公共卫生政策应告知老年 MS 患者 MD 在改善 MS 合并症的心理健康方面的有利影响。

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