Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Department of Medical Ethics and Health Policy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Alzheimers Dement. 2024 Mar;20(3):1527-1537. doi: 10.1002/alz.13558. Epub 2023 Nov 29.
How do reactions to a brain scan result differ between Black and White adults? The answer may inform efforts to reduce disparities in Alzheimer's disease (AD) diagnosis and treatment.
Self-identified Black (n = 1055) and White (n = 1451) adults were randomized to a vignette of a fictional patient at a memory center who was told a brain scan result. Measures of stigma and diagnosis confidence were compared between-groups.
Black participants reported more stigma than White participants on four of seven domains in reaction to the patient at a memory center visit. Black participants' confidence in an AD diagnosis informed by a brain scan and other assessments was 72.2 points (95% confidence interval [CI] 70.4 to 73.5), which was lower than the respective rating for White participants [78.1 points (95%CI 77.0 to 79.3)].
Equitable access to early AD diagnosis will require public outreach and education that address AD stigma associated with a memory center visit.
黑人和白人成年人对脑部扫描结果的反应有何不同？答案可能为减少阿尔茨海默病（AD）诊断和治疗方面的差异提供信息。
自我认同的黑人（n=1055）和白人（n=1451）成年人被随机分配到一个虚构的记忆中心患者的小插曲，该患者被告知脑部扫描结果。在组间比较了对记忆中心就诊患者的反应的七个领域中的四个领域的污名化和诊断信心的措施。
在记忆中心就诊时，黑人参与者对患者的反应在七个领域中的四个领域的污名化程度高于白人参与者。黑人参与者对脑部扫描和其他评估提示 AD 诊断的信心为 72.2 分（95%置信区间[CI]70.4 至 73.5），低于白人参与者的相应评分[78.1 分（95%CI 77.0 至 79.3）]。
要实现早期 AD 诊断的公平获取，需要进行公共宣传和教育，以解决与记忆中心就诊相关的 AD 污名化问题。
