Pilcevic Dejan, Djuric Jovicic Milica, Antonijevic Milos, Bacanin Nebojsa, Jovanovic Luka, Zivkovic Miodrag, Dragovic Miroslav, Bisevac Petar
Clinic for Nephrology, Military Medical Academy, University of Defense, Belgrade, Serbia.
Innovation Center of the School of Electrical Engineering, Belgrade, Serbia.
Front Physiol. 2023 Nov 14;14:1267011. doi: 10.3389/fphys.2023.1267011. eCollection 2023.
Electroencephalography (EEG) serves as a diagnostic technique for measuring brain waves and brain activity. Despite its precision in capturing brain electrical activity, certain factors like environmental influences during the test can affect the objectivity and accuracy of EEG interpretations. Challenges associated with interpretation, even with advanced techniques to minimize artifact influences, can significantly impact the accurate interpretation of EEG findings. To address this issue, artificial intelligence (AI) has been utilized in this study to analyze anomalies in EEG signals for epilepsy detection. Recurrent neural networks (RNNs) are AI techniques specifically designed to handle sequential data, making them well-suited for precise time-series tasks. While AI methods, including RNNs and artificial neural networks (ANNs), hold great promise, their effectiveness heavily relies on the initial values assigned to hyperparameters, which are crucial for their performance for concrete assignment. To tune RNN performance, the selection of hyperparameters is approached as a typical optimization problem, and metaheuristic algorithms are employed to further enhance the process. The modified hybrid sine cosine algorithm has been developed and used to further improve hyperparameter optimization. To facilitate testing, publicly available real-world EEG data is utilized. A dataset is constructed using captured data from healthy and archived data from patients confirmed to be affected by epilepsy, as well as data captured during an active seizure. Two experiments have been conducted using generated dataset. In the first experiment, models were tasked with the detection of anomalous EEG activity. The second experiment required models to segment normal, anomalous activity as well as detect occurrences of seizures from EEG data. Considering the modest sample size (one second of data, 158 data points) used for classification models demonstrated decent outcomes. Obtained outcomes are compared with those generated by other cutting-edge metaheuristics and rigid statistical validation, as well as results' interpretation is performed.
脑电图(EEG)是一种用于测量脑电波和大脑活动的诊断技术。尽管它在捕捉大脑电活动方面具有精确性,但测试过程中的某些因素,如环境影响,会影响脑电图解释的客观性和准确性。即使采用先进技术将伪迹影响降至最低,与解释相关的挑战仍会显著影响脑电图结果的准确解释。为了解决这个问题,本研究利用人工智能(AI)来分析脑电图信号中的异常,以检测癫痫。循环神经网络(RNN)是专门设计用于处理序列数据的人工智能技术,非常适合精确的时间序列任务。虽然包括RNN和人工神经网络(ANN)在内的人工智能方法前景广阔,但其有效性在很大程度上依赖于分配给超参数的初始值,这些初始值对于它们在具体任务中的性能至关重要。为了调整RNN的性能,将超参数的选择作为一个典型的优化问题,并采用元启发式算法来进一步优化这个过程。已经开发并使用了改进的混合正弦余弦算法来进一步改进超参数优化。为了便于测试,使用了公开可用的真实世界脑电图数据。通过从健康受试者采集的数据、确诊为癫痫患者的存档数据以及癫痫发作期间采集的数据构建了一个数据集。使用生成的数据集进行了两个实验。在第一个实验中,表示要检测脑电图活动中的异常。第二个实验要求模型对正常、异常活动进行分段,并从脑电图数据中检测癫痫发作的发生情况。考虑到用于分类模型的样本量较小(一秒的数据,158个数据点),但结果显示出不错的效果。将获得的结果与其他前沿元启发式算法生成的结果以及严格的统计验证结果进行比较,并对结果进行解释。