Department of Stomatology, Taichung Veterans General Hospital, Taichung, Taiwan.
School of Dentistry, National Yang Ming Chiao Tung University, Taipei, Taiwan.
BMC Oral Health. 2023 Dec 6;23(1):969. doi: 10.1186/s12903-023-03551-5.
The chronic systemic inflammatory response in periodontitis may be a potential risk factor for dementia, especially in adults. This study determined the association between periodontal treatment and dementia in adults and evaluated the effect of regular scaling treatment on the risk of dementia in this population.
This case-control study identified 18,930 patients with a dementia-related diagnosis from the Taiwan National Health Insurance Research Database. Scaling and periodontal emergency treatments were evaluated after 1 year and 3 years. Using multivariable logistic regression analysis to evaluate the association between periodontal emergency treatment and dementia risk.
The results showed that scaling treatment rates were lower in the dementia cohort than the non-dementia cohort after 1 and 3 years. Patients who received periodontal emergency treatment within 3 years had a significantly increased risk of dementia. Furthermore, patients with periodontitis who did not receive scaling treatment within 3 years had a higher risk of dementia than patients without periodontitis (OR, 1.22; 95% CI, 1.10-1.35).
This study demonstrated that periodontitis and dementia are associated, and that periodontitis is a risk factor for dementia in adults. The risk of dementia was dependent on the periodontal health status of adults, and our findings suggest that regular scaling can reduce the incidence of dementia in adults. Therefore, regular and routine scaling treatment is suggested for adults.
牙周炎的慢性系统性炎症反应可能是痴呆的潜在危险因素，尤其是在成年人中。本研究旨在确定牙周治疗与成年人痴呆之间的关联，并评估定期洁治治疗对该人群痴呆风险的影响。
本病例对照研究从台湾全民健康保险研究数据库中确定了 18930 名有痴呆相关诊断的患者。在 1 年和 3 年后评估了洁治和牙周急症治疗。使用多变量逻辑回归分析评估牙周急症治疗与痴呆风险之间的关联。
结果显示，在 1 年和 3 年后，痴呆组的洁治治疗率低于非痴呆组。在 3 年内接受牙周急症治疗的患者痴呆风险显著增加。此外，在 3 年内未接受洁治治疗的牙周炎患者比无牙周炎患者患痴呆的风险更高（OR，1.22；95%CI，1.10-1.35）。
本研究表明牙周炎与痴呆有关，且牙周炎是成年人痴呆的危险因素。痴呆的风险取决于成年人的牙周健康状况，我们的研究结果表明，定期洁治可以降低成年人患痴呆的风险。因此，建议成年人定期进行常规洁治治疗。
