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“生命必需 8 要素与美国西班牙裔/拉丁裔成年人偶发高血压:来自西班牙裔社区健康研究/拉丁裔研究的结果。”

Life's Essential 8 and Incident Hypertension Among US Hispanic/Latino Adults: Results From the Hispanic Community Health Study/Study of Latinos.

机构信息

Department of Public Health Sciences University of Miami Miami FL USA.

Smidt Heart Institute, Cedars-Sinai Medical Center Los Angeles CA USA.

出版信息

J Am Heart Assoc. 2023 Dec 19;12(24):e031337. doi: 10.1161/JAHA.123.031337. Epub 2023 Dec 18.

Abstract

BACKGROUND

Life's Essential 8 (LE8) is a new metric to define cardiovascular health. We aimed to describe LE8 among Hispanics/Latinos and its association with incident hypertension.

METHODS AND RESULTS

The HCHS/SOL (Hispanic Community Health Study/Study of Latinos) is a study of Hispanic/Latino adults aged 18 to 74 years from 4 US communities. At visit 1 (2008-2011), information on behavioral and clinical factors (diet, smoking status, physical activity, sleep duration, body mass index, blood pressure, cholesterol, fasting glucose, and medication use) were measured and used to estimate an LE8 score (range, 0-100) for 14 772 participants. Hypertension was defined as systolic blood pressure ≥130 mm Hg or diastolic blood pressure ≥80 mm Hg, or self-reported use of antihypertensive medications. Among the 5667 participants free from hypertension at visit 1, we used Poisson regression models to determine the multivariable adjusted association between LE8 and incident hypertension in 2014 to 2017. All analyses accounted for the complex survey design of the study. Mean population age was 41 years, and 21.6% (SE, 0.7) had high cardiovascular health (LE8 ≥80). Mean LE8 score (68.2; SE, 0.3) varied by Hispanic/Latino background (<0.05), ranging from 72.6 (SE, 0.3) among Mexican Americans to 62.2 (SE, 0.4) among Puerto Ricans. Each 10-unit decrement in LE8 score was associated with a 22% increased risk of hypertension over ≈6 years (incident density ratio, 1.22 [95% CI, 1.16-1.29]).

CONCLUSIONS

Only 1 in 5 Hispanic/Latino adults had high cardiovascular health, and LE8 varied substantially across Hispanic/Latino background groups. Improvements in other components of cardiovascular health may result in a lower risk of developing hypertension.

摘要

背景

Life's essential 8(LE8)是一种新的衡量心血管健康的指标。我们旨在描述西班牙裔/拉丁裔人群中的 LE8,并研究其与高血压发病的相关性。

方法和结果

HCHS/SOL(西班牙裔社区健康研究/拉丁裔研究)是一项针对来自美国 4 个社区的 18 至 74 岁西班牙裔/拉丁裔成年人的研究。在第 1 次就诊(2008-2011 年)时,测量了行为和临床因素(饮食、吸烟状况、身体活动、睡眠时间、体重指数、血压、胆固醇、空腹血糖和药物使用)的信息,并用于估计 14772 名参与者的 LE8 评分(范围 0-100)。高血压定义为收缩压≥130mmHg 或舒张压≥80mmHg,或自述使用抗高血压药物。在第 1 次就诊时无高血压的 5667 名参与者中,我们使用泊松回归模型确定了 2014 年至 2017 年间 LE8 与高血压发病的多变量调整关联。所有分析均考虑了研究的复杂调查设计。人群平均年龄为 41 岁,21.6%(SE,0.7)具有较高的心血管健康水平(LE8≥80)。平均 LE8 评分(68.2;SE,0.3)因西班牙裔/拉丁裔背景而异(<0.05),从墨西哥裔美国人的 72.6(SE,0.3)到波多黎各裔美国人的 62.2(SE,0.4)不等。LE8 评分每降低 10 分,高血压发病风险增加 22%(发生率密度比,1.22[95%CI,1.16-1.29])。

结论

仅有 1/5 的西班牙裔/拉丁裔成年人具有较高的心血管健康水平,LE8 在不同的西班牙裔/拉丁裔背景组之间差异显著。改善心血管健康的其他指标可能会降低患高血压的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e32/10863779/abccec056c3b/JAH3-12-e031337-g001.jpg

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