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自然感染牛流行热群病毒的牛血清中的同源和异源抗体反应。

Homologous and heterologous antibody reactions in sera from cattle naturally infected with bovine ephemeral fever group viruses.

作者信息

Cybinski D H

出版信息

Vet Microbiol. 1987 Jan;13(1):1-9. doi: 10.1016/0378-1135(87)90092-7.

DOI:10.1016/0378-1135(87)90092-7
PMID:3811199
Abstract

Four viruses belonging to the bovine ephemeral fever (BEF) group have been isolated from bovine blood. Infection of cattle with BEF virus was associated with neutralizing antibody responses to BEF, Kimberley (KIM), Berrimah (BRH) and Adelaide River (ADE) viruses, with highest antibody titres to BEF and KIM viruses. Infection of one cow with KIM virus was associated with a homologous neutralizing antibody response and nil or minimal responses to the other three viruses. Infection of a steer with ADE virus was associated with a rise in neutralizing antibody levels to ADE virus and to KIM virus, but not to BEF or BRH viruses. Infection of a steer with BRH virus was associated with marked neutralizing antibody rises to BRH and BEF viruses and small rises to KIM and ADE viruses. An antibody rise to BEF virus did not necessarily indicate recent BEF virus infection, and should be considered of diagnostic value only when taken in conjunction with clinical signs of disease.

摘要

已从牛血液中分离出四种属于牛流行热(BEF)病毒组的病毒。牛感染BEF病毒与针对BEF、金伯利(KIM)、贝里马(BRH)和阿德莱德河(ADE)病毒的中和抗体反应有关,其中对BEF和KIM病毒的抗体滴度最高。一头牛感染KIM病毒与同源中和抗体反应有关,而对其他三种病毒的反应为零或极小。一头公牛感染ADE病毒与针对ADE病毒和KIM病毒的中和抗体水平升高有关,但与BEF或BRH病毒无关。一头公牛感染BRH病毒与针对BRH和BEF病毒的显著中和抗体升高以及针对KIM和ADE病毒的小幅升高有关。对BEF病毒的抗体升高不一定表明近期感染了BEF病毒,只有与疾病的临床症状相结合时才应被视为具有诊断价值。

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